摘要
低分子肝素(LMWH)作为一种有效的抗凝剂,常用于预防或治疗深部静脉血栓和肺栓塞等疾病,临床主要采用注射给药。本文综述近年来LMWH非注射给药途径及分析方法研究进展。
As an effective anticoagulant, low molecular weight heparin (LMWH) is usually chosen to prevent and treat deep vein thrombosis (DVT) and pulmonary embolism (PE). However, it is used by frequent injection in clinic due to its short half-life and poor bioavailability. This review summarizes nonparenteral administration routes and their analytical methods.
出处
《世界临床药物》
CAS
2010年第11期676-681,共6页
World Clinical Drug
基金
国家"重大新药创制"科技重大专项(2009ZX09310-003)
关键词
低分子肝素
非注射给药途径
分析方法
low molecular weight heparin
nonparenteral administration route
analytical method