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Not miR-ly aging: SIRT1 boosts memory via a microRNA- dependent mechanism

Not miR-ly aging: SIRT1 boosts memory via a microRNA- dependent mechanism
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摘要 Long-term memory formation requires new synthesis of proteins that regulate synaptic plasticity. Recently, microRNAs (rniRNAs) have been identified as master regulators of protein synthesis, miRNAs are an extensive class of small noncoding RNAs (21-25 nt) that preferentially bind to the 3' un- translated regions (UTRs) of mRNAs, thereby either inducing translational repression or degradation of the target mRNA. In the nervous system, miRNAs control diverse processes,
出处 《Cell Research》 SCIE CAS CSCD 2010年第11期1175-1177,共3页 细胞研究(英文版)
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参考文献11

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