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空回肠出血的病因和临床特征分析 被引量:3

Etiology and clinical features of jejunoileum bleeding
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摘要 目的 探讨空回肠出血的病因及临床特点.方法 收集山东省7个地市级医院1998年1月至2008年12月空回肠出血住院患者72例,其中男46例,女26例,年龄13~85岁,平均47岁.所有患者空回肠出血经内镜、影像学或手术确诊.回顾性分析空回肠出血的病因、诊断及主要临床表现等.结果 72例空回肠出血患者中,肿瘤为出血常见病因,占58.3%,42/72,其他依次为炎症(9/72,12.5%)、憩室(7/72,9.7%)、血管病变(7/72,9.7%)、克罗恩病(3/72,4.2%).男、女病因构成比及空肠、回肠出血病因构成比间差异均有统计学意义(P值均<0.05).首发症状及临床表现以便血和便血伴腹痛为主.手术仍是目前确诊的主要手段(54.2%),其次为胶囊内镜(23.6%)、选择性动脉造影(9.7%)、小肠气钡X线造影(6.9%)、结肠镜(2.8%)和小肠镜(2.8%).伴随症状出现频率依次为贫血、肠梗阻、腹腔脏器转移、休克、肠粘连、肠穿孔.结论 小肠肿瘤是引起空回肠出血的主要原因,且主要位于空肠;而炎症、血管畸形和憩室则主要位于回肠.应加强胶囊内镜和小肠镜在临床中的应用. Objective To evaluate the etiology and clinical features of jejunoileum bleeding.Methods Seventy-two patients admitted in 7 hospitals of Shangdong province for jejunoileum bleeding from January 1998 to December 2008 were enrolled in the study. There were 46 males and 26 females with mean age of 47 years (ranged 13-85 years). The jejunoileum bleeding was confirmed by means of endoscopy, images or surgery. The causes, diagnostic methods and major clinical manifestations were retrospectively analyzed. Results The most frequent cause of jejunoileum bleeding was tumor (42/72,58.3 %), followed by enteritis (9/72, 12.5 %), diverticulum ( 7/72, 9. 7%), angiopathy (7/72,9.7%), Crohn's disease (3/72,4.2%). Differences were significant in constituent ratio of cause of jejunoileum hemorrhage between male and female and between jejunum and ileum (P<0.05).Hematochezia or hematochezia with abdominal pain was the first presentation. The jejunoileum bleeding in 54. 2% patients was diagnosed by laparotomy, 23. 6% by capsule endoscopy, 9.7% by selective angiography, 6.9% by small bowel series and enteroclysis, 2.8% by colonoscopy and 2.8% by push enteroscopy. The complications of jejunoileum bleeding were anemia, intestinal obstruction,peritoneal metastasis, shock, ankylenteron and intestinal perforation. Conclusions Intestinal tumor is the most common cause in jejunoileum bleeding, especially in jejunum. Whereas the enteritis,diverticulum and angiopathy were often found in ileum. The capsule endoscopy and push enteroscopy are recommended in diagnosis of jejunoileum bleeding.
出处 《中华消化杂志》 CAS CSCD 北大核心 2010年第9期577-580,共4页 Chinese Journal of Digestion
关键词 胃肠道出血 空肠 回肠 病因 体征和症状 Gastrointestinal hemorrhage Jejunum Ileum Etiology Signs and symptoms
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同被引文献26

  • 1Tomoaki Matsumura,Makoto Arai,Toru Sato,Tomoo Nakagawa,Daisuke Maruoka,Masaru Tsuboi,Sachio Hata,Eiji Arai,Tatsuro Katsuno,Fumio Imazeki,Osamu Yokosuka.Efficacy of computed image modification of capsule endoscopy in patients with obscure gastrointestinal bleeding[J].World Journal of Gastrointestinal Endoscopy,2012,4(9):421-428. 被引量:4
  • 2许卫兵,邹晓平,徐肇敏,李运红,卢晓云.胶囊内镜诊断小肠血管发育不良40例[J].中华消化内镜杂志,2006,23(6):441-442. 被引量:4
  • 3冉志华,沈谋绩,萧树东.50例小肠出血病因及诊断分析[J].中华消化杂志,1996,16(2):66-68. 被引量:69
  • 4Cellier C. Obscure gastrointestinal blecding:role of videocapsule and double-balloon enteroscopy[J].Best Practice and Research in Clinical Gastroenterology,2008,(2):329-340.doi:10.1016/j.bpg.2007.12.006.
  • 5Pasha S,Leighton J,Das A. Diagnostic yield and therapeutic utility of double-halloon enteroscopy (DBE) in patients with obscure gastrointestinal bleeding (OGIB):a systematic review[J].Gastrointestinal Endoscopy,2007.AB366.doi:10.1016/j.gie.2007.03.952.
  • 6Gra(c)a BM,Freire PA,Brito JB. Gastroenterologic and radiologic appnoach to obscurc gastrointestinal bleeding:how,why,and when[J].Radiographics:A Review Publication of the Radiological Society of North America,Inc,2010.235-252.
  • 7Ghosh S,Watts D,Kinnear M. Management of gastrointestinal hemorrhage[J].Postgraduate Medical Journal,2002,(915):4-14.doi:10.1136/pmj.78.915.4.
  • 8Delvaux M,Fassler I,Gay G. Clinical usefulness of the endoscopic video capsule as the initial intestinal investigation in paticnts with obscure digestive bleeding:validation of a diagnostic strategy based on the patient outcome after 12 months[J].Endoscopy,2004,(12):1067-1073.doi:10.1055/s-2004-826034.
  • 9Vere CC,Foarfǎ C,Streba CT. Videocapsule endoscopy and singlc balloon enteroscopy:novel diagnostic techniques in small bowel pathology[J].Romanian Journal of Morphology and Embryology,2009.467-474.
  • 10Matsumura T,Arai M,Sazuka S. Negative capsule endoscopy for obscure gastrointestinal bleeding is closely associated with the use of low-dose aspirin[J].Scandinavian Journal of Gastroenterology,2011.621-626.doi:10.3109/00365521.2010.545833.

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