摘要
目的探讨单纯疱疹毒性脑炎（HSVE）的临床表现及治疗现状。方法经ABC－ELISA法检测血和脑脊液单纯疱疹病毒抗体（HSVAb）确定的HSVE31例，男18例，女13例，平均年龄32±11岁。结果HSVE临床症状变异很大，有全身感染症状，脑膜刺激症状，脑症状，精神症状等。结论ELISA法检测HSV－1抗体对于HSVE早期诊断有一定价值，而PCR诊断HSVE较ELISA敏感性高，速度快，但PCR敏感性太高，极易造成假阳性，操作较复杂，ELISA法操作简便，宜于广泛应用。阿昔洛韦是目前治疗HSVE较理想的药物，但宜早期应用。
Purpose Approach the clinical expression and therapeutic present situation of herper simplex virus encephalitis (HSVE).Method Thiry-one cases were defined with Herper Simplex Virus Encephalitis after the examination of blood and cerebrospinal flnid (SF)CHSV-Ab in the way of ABC-ELASA(male18, female 13, average age32 ±11). Result HSVE clinical symptom greatly varied. There are infection all over the body, meninx incentive, brain symptom and morality symptom,etc. Conclusion It is valuable to the early treatment of HSVE to examine HSV-1 antibody in the way of ELASA. But the susceptibility of PCR treatment to HSVE is higher thar than of ELASA,the same with the speed. However, the susceptibility of PCR is so high that it's easy to occur false positive reaction and operation is more complex. ELAS iseasy to operate and can be widely used. Aciclovir is ideal in cure of HSVE, but it is better to be used earlier.
出处
《河南实用神经疾病杂志》
1999年第2期3-4,共2页
Henan Journal of Practical Nervous Diseases
