摘要
目的对奥美拉唑和泮托拉唑治疗消化道溃疡进行药物经济学分析,为临床合理用药提供参考方案。方法采用统计学研究和成本-效果分析方法 ,将我院100例良性消化道溃疡患者,随机分为A组及B组,A组给予奥美拉唑,B组给予泮托拉唑,比较两组的成本-效果及不良反应。结果两组总有效率分别为94%和96%,效果无显著差异(P>0.05),治疗成本分别为523.00元和445.20元,差异显著(P<0.05),进行敏感度分析,结果仍相符。两组不良反应均以胃肠道反应为主。结论 B组成本-效果较好,从经济学角度考虑,B组比A组更经济合理。
Objective Omeprazole and pantoprazole for treatment of peptic ulcer drugs,economic analysis,provide a reference for the clinical program of rational drug use. Methods The statistical studies and cost -effectiveness analysis,will be in our hospital 100 cases of benign ulcer were randomly divided into A group and B group,A group received omeprazole,B group received pantoprazole,compare the cost of the two groups -and adverse response. Results The total effective rate were 94% and 96% ,there were no significant difference （ P 0. 05） ,treatment costs were 523. 00 yuan and 445. 20 yuan,there were significan difference （ P 0. 05） ,the sensitivity analysis,the results still consistent. Two groups of adverse reactions were gastrointestinal reactions. Conclusion B group have a good cost effectveness. From the economic point of view,B group than in the A group is more economical.
出处
《中国现代药物应用》
2010年第21期15-16,共2页
Chinese Journal of Modern Drug Application
