摘要
目的:观察自拟降浊逐瘀汤治疗高脂血症的临床效果。方法:127例高脂血症患者被随机分为两组:治疗组(65例)给予自拟浊逐瘀汤治疗;对照组:(62例)给予口服脂必妥片,两组连续治疗2个月。检测治疗前后两组患者血脂水平、血液流变学变化,不良反应,并判断临床疗效。结果:经过治疗后,两组患者总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)水平无显著性差异(P>0.05);经过治疗后,两组患者血浆比黏度(RPV)、血球压积(HCT)、血小板黏附率(PAD)亦无显著性差异(P>0.05)。治疗组总有效率为90.77%,对照组总有效率为91.94%,两组无显著性差异。治疗组未见不良反应。结论:自拟降浊逐瘀汤能明显改善血脂代谢,是疗效确切、应用安全的汤剂。
Objective：To observe the effect of self-prescribed decoction of reducing turbidity and removing stasis on patients with hyperlipemia. Methods：127 patients with hyperlipemia were randomly divided into two groups：treatment group （ 65 patients） and control group （ 62 patients）. The patients in treatment group received with self-prescribed decoction,whereas the patients in control group were given with Zhibituo tablets for oral administration. After two months therapy,serum lipids and of changes in hemorheology of patients were analyzed and side-effects were observed. Results：No significant difference was observed in the levels of total cholesterol （ TC） ,triglyeride TG） ,low density lipoprotein cholesterol （ LDL-C） and high density lipoprotein cholesterol （ HDL-C） between two groups after the treatment （ P 0. 05）. Moreover,there was no significant difference in plasma relative viscosity （ PRV） ,hematocrit （ HCT） ,platelet adhesion rate （ PAD） between two groups after the treatment （ P 0. 05）. Total effective rate of treatment group and control group were 90. 77% and 91. 94% ,respectively,and no obvious difference was detected between the two groups （ P 0. 05）. No side-effects were observed in treatment group. Conclusion：Self-prescribed decoction of reducing turbidity and removing stasis improves blood lipid metabolism remarkably with definite therapeutic effect and safety in application.
出处
《辽宁中医杂志》
CAS
北大核心
2010年第11期2184-2185,共2页
Liaoning Journal of Traditional Chinese Medicine
关键词
高脂血症
自拟汤荆
血脂
血液流变学
hyperlipemia self-prescribed decoction blood lipid hemorheology
