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药品不良反应及其机制探讨 被引量：3

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摘要 药品对机体的作用具有两重性，一方面是治疗作用，另一方面是不良反应。自1877年英国医学会报道了当时广泛用于全身麻醉的氯仿具有严重的呼吸和心脏毒性的消息后，药品不良反应（ADR）开始引起了人们的关注。20世纪60年代初，震惊世界的“反应停（thalidomide）”事件促使许多国家建立了各种药品不良反应监测机构，开展了ADR及其流行病学的研究。
作者 张静 李国芬
机构地区 辉瑞(中国)研究开发有限公司安全与风险管理部
出处 《药物流行病学杂志》 CAS 2010年第11期641-645,共5页 Chinese Journal of Pharmacoepidemiology
关键词 药品不良反应 机制
分类号 R181.35 [医药卫生—流行病学]
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参考文献10

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二级参考文献11

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共引文献13

同被引文献23

  • 1陈崇泽,李榕.建立医院药品不良反应监测系统及工作体会[J].中国药物警戒,2004,1(2):55-56. 被引量：5
  • 2李榕,陈崇泽.医院药品不良反应监测模式的探讨[J].中国药物警戒,2006,3(1):53-55. 被引量：8
  • 3于滢.卡托普利的不良反应分析[J].天津药学,2007,19(1):37-39. 被引量：6
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引证文献3

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药物流行病学杂志
2010年 第11期

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