4Niirama K,Endo H, Chan P H. Oxidative stress and mitoehondrial dysfunction as determinant8 of isehemie neuronal death and surviv- al[ J]. J Neuroehera,2009,109 ( Suppl 1 ) : 133-138.
5Lapchak P A, Aranjo D M. Advances in ischemic stroke treatment: neuroprotective and combination therapies [ J ]. Exp Opin EmergDrugs ,2007,12( 1 ) :97-112.
6Edaravone Acute Infarction Study Group. Effect of a novel free rad- ical scavenger, edaravone ( MCI-186 ), on acute brain infarction. Randomized, placebo-controlled, double-blind study at muhicenters [ J ]. Cerebrovasc Dis,2003,15 ( 3 ) :222 -229.
7Toyoda K, Fujii K, Kamouchi M, etal. Free radical scavenger, edaravone, in stroke with internal carotid artery occlusion [ J ]. J Neurol Sci,2004,221 (1/2) :11-17.
9Kawasaki T, Kitao T, Nakagawa K, et al. Nitric oxide-induced ap- optosis in cultured rat astrocytes:protection by edaravone, a radical scavenger[ J ]. Glia,2007,55 ( 13 ) : 1325-1333.
10Yamashita T, Kamiya T, Deguchi K, et al. Dissociation and protec- tion of the neurovascular unit after thrambolysis and reperfusion in ischemic rat brain[J]. J Cereb Blood Flow Metab,2009,29 ( 4 ) : 715-725.