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急性冠脉综合征早期静脉应用美托洛尔对生命体征及心率变异性的影响 被引量:4

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摘要 目的研究急性冠脉综合征(ACS)早期应用美托洛尔注射液对患者心率、血压、心率血压乘积及心率变异性(HRV)的影响。方法收集住院的ACS患者53例,随机分为治疗组和对照组。治疗组26例,入院即在心电血压监护下缓慢分次静推美托洛尔注射液,对照组采用常规治疗。分别测定入院时治疗后两组心率、血压变化。两组患者均于出院时做24 h动态心电图检查。结果治疗组使用美托洛尔注射液后血压较对照组入院后3 0 min时下降,两组分别为(106.17±1 6.5)mmHgvs(1 2 4.2 6±1 6.8 9)mmHg(P<0.0 5);心率血压乘积较对照组入院后3 0 min时下降,两组分别为(8 0 6 5.1 1±1 7 7 9.6 7)vs(1 0 0 5 0.8 9±2 7 7 9.3 3,P<0.05);两组心率比较虽可看到治疗组有下降趋势(75.62±13.47)/min vs(80.56±17.51)/min,但无统计学意义。两组于出院时的HRV各时域指标比较无明显区别。结论 ACS早期应用美托洛尔注射液可明显减慢心率,降低血压,减少了心率和血压的乘积,达到阻断交感神经作用。
出处 《中西医结合心脑血管病杂志》 2010年第11期1297-1299,共3页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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