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1%吡美莫司乳膏治疗阴囊湿疹疗效观察 被引量:5

Efficacy Observation of 1% Pimecrolimus Ointment in Treatment of Scrotum Eczema
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摘要 目的探讨1%吡美莫司乳膏治疗阴囊湿疹的疗效及安全性。方法通过随机数字表法将82例患者分为两组,对照组40例,采用百癣夏塔热片治疗,3片/次,3次/d;治疗组42例,在百癣夏塔热片治疗的基础上外用1%吡美莫司乳膏,2次/d,连用21天。结果治疗组第7天、第14天和第21天的有效率分别为45.23%,69.05%和76.19%,优于对照组的37.50%,45.00%和52.50%。两组第14天和第21天的有效率比较差异有统计学意义(P均<0.05)。患者均未出现严重的不良反应。结论 1%吡美莫司乳膏治疗阴囊湿疹有良好的效果,不良反应少。 Objective To observe the efficacy and safety of 1% pimecrolimus ointment in the treatment of scrotum eczema. Method According to random number table, eighty-two patients were divided into two groups. Forty patients of control group were treated with baixuanxiatare tablets three pills once , three times a day. Forty- two patients in the treatment group were treated with 1% pimecrolimus cream twice a day combining with baixuanxiatare. Results Effective ratio of the treatment group on the 7th day, 14th day and 21 st day were 45. :23% ,69.05% and 76.19% respectively, while that of the control group were 37.50% ,45.00% and 52.50%. Statistical significance was found between the two groups on the 14th day and 21st day(P 〈 0. 05). No serious adverse events were recorded in both groups. Conclusion 1% pimecrolimus ointment in the treatment of scrotum eczema is effective and safe.
出处 《中国皮肤性病学杂志》 CAS 北大核心 2010年第11期1076-1077,共2页 The Chinese Journal of Dermatovenereology
关键词 阴囊湿疹 吡美莫司乳膏 Scrotum eczema Pimecrolimus ointment
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参考文献5

  • 1彭安厚.复方氟米松软膏治疗掌跖部慢性湿疹临床观察[J].中国皮肤性病学杂志,2008,22(5):318-319. 被引量:25
  • 2林常红.中西医结合治疗阴囊湿疹72例[J].现代中西医结合杂志,2003,12(8):826-826. 被引量:4
  • 3Hoetzenecker W,Meingassner JG,Ecker R,et al.Corticosteroids but not pimecrolimus affect viability,maturation and immune function of murine epidermal Langerhans cells[J].J Invest Dermatol,2004,122(3):673-684.
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二级参考文献3

  • 1孙建方,郑志忠,顾军,曾学思,付雯雯,毕新岭.0.05%地奈德乳膏治疗湿疹的多中心随机双盲、对照研究[J].中华皮肤科杂志,2006,39(1):26-28. 被引量:79
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