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急诊静脉溶栓治疗急性心肌梗塞41例临床观察

Clinical observation on intravenous thrombolytic therapy of acute myocardial infarction in the Emergency Department:Report of 41 Cases
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摘要 目的:总结急性心肌梗塞急诊溶栓效果。方法:使用rt-PA、SK急诊静脉溶栓41例。结果:再通率70.7%(29/41),<70岁组及≥70岁组再通率无显著差异。未通组与再通组出血、低血压发生无差异,而Kilip≥Ⅲ级以上、严重心律失常、一周内病死率及梗后心绞痛,未通组明显高于再通组。11例出现再灌注心律失常。结论:溶栓治疗能保护心功能,改善预后。对70岁以上AMI仍应积极溶栓治疗。应用地塞米松可减少SK的副作用。要警惕早期溶栓恶性心律失常的出现。为进一步提高溶栓效果,积极提倡推广急诊溶栓。 Objective:To evaluate the effect of intravenous thrombolytic therapy on acute myocardial infarction(AMI)in the emergency departmentMethods:Fortyone cases of AMI was injected intravenously with 100mg rtPA and 15million u streptase (SK) in the EICUResults:Reperfusion rate was 707%(29/41),reperfusion rate showed no significant differences between below 70 yearold group and over 70 yearold group,hemorrhage(mild bleeding) and hypotension showed no significant differences between reopened group and unopened group,but cardiac function grade killip or over,cardiac arrhythmia,mortality rate in the first week,and argina pectoris after AMI in unopened group were significantly higher than that in opened group11 cases occurred reperfusion arrhAuthor ythmiaConclusion:Thrombolytic therapy can protect cardiac function and improve the prognosisIt is positive that thrombolytic therapy is given to over 70 yearold patients of AMIDexamethasone can relieve the side effects of SKIt should be keep in the mind that cardiac arrhythmia may occur in early stageIt was suggested that intravenous thrombolytic therapy of AMI should be carried out and expended in the emergency department in order to increase effect of that
作者 骆雪萍 王钢
出处 《广西医学》 CAS 1999年第3期395-398,共4页 Guangxi Medical Journal
关键词 静脉溶栓 急诊 心肌梗塞 AMI 治疗 Intravenous thrombolytic therapy Emergency treaemtnt Acute myocardial infarction
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