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脾虚小鼠红细胞免疫和腹腔巨噬细胞吞噬功能改变的实验研究 被引量:26

Experimental Study on the Erythrocyte Immunization and Phagocytic Change of Celiac Macrophagocyte in the Mouse Model with Deficient Spleen Syndrome
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摘要 采用化学发光测定和分析的方法,对利血平造模的小鼠进行腹腔巨噬细胞吞噬功能和红细胞免疫功能的测定。结果:脾虚证小鼠腹腔巨噬细胞吞噬功能和红细胞免疫功能下降。 Objective: Test the phagocytic function of celiac macrophagocyte and the erythrocyte immunization, to study the essence of deficient spleen syndrome from the perspective of nonspecific immunity. Methods: Using chemiluminescence assay to determine phagocytic function of celiac macrophagocyte and the erythrocyte immunization of the mouse model by reserpine. Results: The phagocytic function of celiac macrophagocyte and the erythrocyte immunization were decreased in the deficient spleen mouse model. After treating with Sijunzi Tang which can invigorate the spleen and replenish qi in TCM, the phagocytic function of celiac macrophagocyte and the erythrocyte immunization were markedly restored and enhanced. Conclusion: the decreased nonspecific immunologic function of deficient spleen syndrome provide a fresh database for the study on the essence of deficient spleen syndrome in the immunologic function.
出处 《北京中医药大学学报》 CAS CSCD 北大核心 1999年第3期26-27,共2页 Journal of Beijing University of Traditional Chinese Medicine
基金 国家自然科学基金
关键词 脾虚 腹腔巨噬细胞 吞噬 红细胞免疫 四君子汤 Deficient spleen syndrome Celiac macrophagocyte Phagocytic function Erythrocyte immunization Sijunzi Tang
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