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Ⅲ期胃癌新辅助化疗效果的临床分析 被引量：3

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摘要 目的探讨新辅助化疗对Ⅲ期胃癌患者的疗效。方法胃恶性肿瘤患者130例,分为新辅助化疗组(NAC组)65例,常规化疗组(CC组)65例,比较两组患者区域淋巴结彻底清除率(R0切除率)、复发率及生存率。结果与CC组相比,NAC组的R0切除率高于CC组(P<0.05);NAC组的复发率术后12、24月低于CC组(P<0.05),NAC组的病死率术后6、12、24月低于CC组(P<0.05)。结论Ⅲ期胃癌新辅助化疗对提高患者R0切除率,降低胃癌术后复发率及病死率,效果优于传统的手术加术后化疗。
作者 周堃 纪俊标
机构地区 南京医科大学附属江宁医院普通外科
出处 《江苏医药》 CAS CSCD 北大核心 2010年第19期2333-2334,共2页 Jiangsu Medical Journal
关键词 胃癌 新辅助化疗 R0切除率
分类号 R735 [医药卫生—肿瘤]
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  • 1屈涛.血清半胱氨酸、维生素B2水平与食管癌及胃贲门癌相关[J].中国医学论坛报，肿瘤专刊,2001,.
  • 2李连弟,鲁凤珠,张思维,牧人,孙秀娣,皇甫小梅,孙杰,周有尚,欧阳宁慧,饶克勤,陈育德,孙爱明,薛志福,夏毅.中国恶性肿瘤死亡率20年变化趋势和近期预测分析[J].中华肿瘤杂志,1997,19(1):3-9. 被引量：869
  • 3WHO. 1994 World Health Statistics Annual. Geneve: WHO, 1995 ,B4-B347.
  • 4Limburg P, Qiao Y, Mark S, et al. Helicobacter pylori seropositivity and subsite-specific gastric cancer risks in Linxian, China. J Natl Cancer.Inst, 2001,93:226-233.
  • 5Pisani P, Parkin DM, Ferlay J, et al. Estimates of the worldwide mortality from 25 cancers in 1990. Int J Cancer, 1999,83: 18-29.
  • 6WHO. 1973-1976 World Health Statistics Annual. Geneve: WHO,1976. 188-719.
  • 7Christoforidis E,Kanellos I,Tsachalis T,et al.Locally recurrent rectal cancer after curative resection.Tech Coloproctol,2004,8( Suppl 1):s132-134.
  • 8Piso P,Dahlke MH,Mirena P,et al.Total mesorectal excixion for middle and lower rectal cancer:a single inotitution experience with 337 consecutive patients.J Surg Oncol,2004,86(3):115-224.
  • 9Vironen JH,Halme L,Sainio P,et al.New aproaches in the management of rectal carcinoma result in reduced local recurrence rate and improved survival.Eur J Surg,2002,168(3):158-164.
  • 10Frei E 3rd.Clinical cancer research:an embattled species.Cancer,1982,50(10):1979-1992.

共引文献1158

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  • 1Roberto Biffi,Nicola Fazio,Fabrizio Luca,Antonio Chiappa,Bruno Andreoni,Maria Giulia Zampino,Arnaud Roth,Jan Christian Schuller,Giancarla Fiori,Franco Orsi,Guido Bonomo,Cristiano Crosta,Olivier Huber.Surgical outcome after docetaxel-based neoadjuvant chemotherapy in locally-advanced gastric cancer[J].World Journal of Gastroenterology,2010,16(7):868-874. 被引量：44
  • 2Cheng-WuZhang,Shou-ChunZou,DunShi,Da-JianZhao,Cheng-WuZhang.Clinical significance of preoperative regional intra-arterial infusion chemotherapy for advanced gastric cancer[J].World Journal of Gastroenterology,2004,10(20):3070-3072. 被引量：31
  • 3Ferro A, Peleteiro B, Malvezzi M ,et al. Worldwide trends in gastric cancer mortality( 1980 - 2011 ), with predictions to 2015, and inci- dence by subtype[J]. Eur J Cancer,2014,50(7):1330-1344.
  • 4Ferlay J,Parkin DM,Steliarova-Foucher E. Estimates of cancer in- cidence and mortality in Europe in 2008 [ J]. Eur J Cancer,2010, 46(4) :765 -781.
  • 5Nob SH, Park SR, Yang HK, et al. Adjuvant capecitabine plus ox- aliplatin for gastric cancer after D2 gastrectomy (CLASSIC) : 5 - year follow-up of an npen-label, randomised phase 3 trial[ J ]. Lan- cet Oncol,2014,15 ( 12 ) : 1389 - 1396.
  • 6Patru CL, Surlin V, Georgescu I, et al. Current issues in gastric cancer epidemiology [ J ]. Rev Med Chir Soc Med Nat Iasi,2013, 117( 1 ) :199 -204.
  • 7Ma SC, Zhao Y, Zhang T, et al. Association between the ERCC1 rsl1615 polymorphism and clinical outcomes of oxaliplatin-based chemotherapies in gastrointestinal cancer:a meta-analysis[ J ]. Onco Targets Ther,2015 ,8 :641 -648.
  • 8Song P, Yin Q, Lu M, et al. Prognostic value of excision repair cross- eomplementation group 1 expression in gastric cancer: A meta-analy- sis[J]. ExpTher Med,2015,9(4): 1393-1400.
  • 9Kim KH,Kwon HC, Oh SY, et al. Clinicopathologic significance of ERCC1, thymidylate synthase and glutathione S - transferase P1 ex- pression for advanced gastric cancer patients receiving adjuvant 5 - FU and cisplatin chemotherapy [ J ]. Biomarkers, 2011,16 ( 1 ) : 74 - 82.
  • 10Kwon HC,Roh MS, Oh SY, et al. Prognostic value of expression of ERCC1, tbymidylate synthase, and glutathione S -transferase PI for 5 -fluorouracil/oxaliplatin chemotherapy in advanced gastric cancer[ J ]. Ann Oncol,2007,18 ( 3 ) :504 - 509.

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江苏医药
2010年 第19期

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