摘要
目的：了解运动神经元病（ＭＮＤ）患者认知障碍的特点。方法：采用韦氏成人智力量表、临床记忆量表和体感刺激诱发的事件相关脑诱发电位，对１８例ＭＮＤ患者和２４例健康人进行了测验比较。结果：ＭＮＤ患者可出现不同程度的智能、记忆障碍。其中语言智商（３３．３％）、操作智商（３８．９％）、全量表智商（２７．８％）和记忆商（３８．９％）在边界以下。本组患者表现为皮质兼皮质下智能障碍的特征。其认知电位Ｐ３００的潜伏期与对照组相比明显延长（ｐ＜０．００１），波幅明显降低（ｐ＜０．００１）。
Objective:to investigate characteristics of cognitive disturbance in patients with motor neuron disease(MND) Method:18 patients with MND and 24 normal subjects were tested with Wechsler Adult Intelligence Scale,Clinic Memory Scale and Event related potential(ERP) Result:patients with MND manifested disturbance of intelligence and memory at various degrees 38 9% patients had memory quotient(MQ) less than 80,27 8% with intelligence quotient(IQ) less than 80,33 3% with verbal quotient(VIQ) less than 80,and 38 9% with processing quotient(PIQ) less than 80 Patient with MND had prolonged N2 and P300 latencies and lowered P300 amplitude compared with normal controls Conclusion:the result of this study give us some implication for the early diagnosis of intelligent deficiency in patients with MND
出处
《中国心理卫生杂志》
CSSCI
CSCD
北大核心
1999年第3期180-181,共2页
Chinese Mental Health Journal
