期刊文献+

依达拉奉治疗急性脑梗死的临床疗效观察 被引量:12

依达拉奉治疗急性脑梗死的临床疗效观察
暂未订购
导出
摘要 目的探讨依达拉奉注射液(必存注射液)对治疗急性脑梗死的疗效。方法选择发病72h内的急性脑梗死患者158例,随机分为必存组(79例)和对照组(79例),分别于治疗前和治疗后2周进行临床疗效和神经缺失分数减少程度评定。结果治疗2周后,必存组总有效率为92.41%;对照组总有效率为77.22%,两组相比差异具有统计学意义(P<0.01)。结论依达拉奉对急性脑梗死患者有较好的疗效,值得推广应用。 Objective To explore the effects of edaravone on acute cerebral infarction(ACI) patients.Methods 158 ACI patients who had an onset with in 72 hours were allocated to edaravone group(79 cases) and the control group(79 cases).The clinical effect and the degree of nerve defscit cores were used in the two groups befour treatment and after.Results The effective point were 92.41% with edaravone group after 2 weeks,and the effective point were 77.22% with the control group,There was a significant difference in the two groups(P 0.01).Conclusion Edaravone has a higher curative effect with ACI,it is worthy to be recommended for clinical application.
作者 李皓亮
出处 《中国现代药物应用》 2010年第20期13-14,共2页 Chinese Journal of Modern Drug Application
关键词 必存 急性脑梗死 临床疗效 Edaravone Acute cerebral infarction Clinical curative effect
  • 相关文献

参考文献8

二级参考文献5

  • 1刘伟国,杨小锋,李谷,徐锦芳,徐晓燕.依达拉奉抗急性脑出血自由基反应的研究[J].浙江创伤外科,2006,11(1):1-3. 被引量:26
  • 2Zhang N,Komine-Kobayashi M,Tanaka R,et al.Edaravone rduces early accumulation of oxidative products and sequential inflammtory responses after transient focal ischemia in mice brain[J].Stroke,2005,36 (10):2220-2225.
  • 3Wen J,Watanabe K,Ma M,et al.Edaravone inhibits JNK-cJun pathway and restores anti-oxidative defense after ischemia-reperfusion injury in aged rats[J].Biol Pharm Bull,2006,29 (4):713-718.
  • 4Nakamura H,Uzura M,Uchida K,et al.Effects of edaravone on experimental brain injury in view of free radical reaction[J].Acts NeurochirSuppl,2003,86:309-311.
  • 5Eiichi O.Effect of a novel free radical scavenger,Edaravone (MCI-186),on acute brain infarction[J].Cerebrovasc Dis,2003,15(3):222-229.

共引文献43110

同被引文献152

引证文献12

二级引证文献138

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部