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特发性血小板减少性紫癜86例治疗体会

Treatment of 86 Cases Idiopathic thrombocytopenic Purpura
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摘要 目的总结和比较特发性血小板减少性紫癜(ITP)的三组治疗方法。方法对2005年1月—2009年6月商丘市第一人民医院血液科收治86例ITP患者随机分为IVIG(丙种球蛋白)组,泼尼松组,IVIG及泼尼松联合用药组三个治疗组,比较其疗效。结果联合用药组出血症状控制时间最短,与IVIG组比较无差异(P>0.05);与泼尼松组比较有统计学意义(P<0.01);IVIG组的血小板达到有效的时间最快,与另两组相比差异有统计学意义(P<0.01);2周后血小板计数比较,联合用药组效果最好,联合用药组与波尼松组和IVIG组比较有统计学意义(P<0.01)。结论大剂量免疫球蛋白联合糖皮质激素治疗ITP是一种能快速而明显升高血小板、快速控制出血的疗效确切的治疗方法。 Objective To review and compare with idiopathic thrombocytopenic purpura (ITP), three groups of treatment. Methods January 2005 - June 2009 86 cases were treated in our hospital Hematology ITP were randomly assigned to IVIG gamma globulin) group, and the prednisone group, IVIG and prednisone combined group of three treatment groups, Comparison of the effect. Results The combined treatment group has the shortest bleeding control, and compared with the IVIG group (P 〉 0.05) ; and compared with prednisone group (P 〈0.01 ) ; IVIG group the fastest time of platelets compared with the other two groups. There was significant difference (P 〈 0. 01 ) ; 2 weeks later the platelet count combination group is best, compared with the prednisone group and the IVIG group (P 〈 0.01 ). Conclusion Large dose of immune globulin and corticosteroids for ITP can lastly and significantly increase platelets, rapid control Of bleeding.
作者 陈淑霞
出处 《医药论坛杂志》 2010年第18期70-71,共2页 Journal of Medical Forum
关键词 特发性血小板减少性紫癜 泼尼松 丙种球蛋白 疗效 Idiopathic thrombocytopenie purpura Prednisone Gamma globulin Effect
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