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新辅助化疗对胃癌术后吻合口瘘发生率的影响

Influence of Neo-adjuvant Chemotherapy on Rate of Anastomic Leak Post Gastrectomy
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摘要 目的探讨新辅助化疗对胃癌术后并发症吻合口瘘发生率的影响。方法对156例进展期胃癌分为对照组与新辅助化疗组后实施手术,新辅助化疗组术前应用FOLFOX6方案化疗,对两组切除术后吻合口瘘发生率进行比较。结果对照组与新辅助化疗组吻合口瘘发生率差异不具有统计学意义。结论新辅助化疗没有增加胃癌切除术后吻合口瘘发生率。 Objective To evaluatethe effect of neo anastomotic leak in post gastrectomy occurrence. Methods -adjuvant chemotherapy on the rate of Totally 156 cases of advanced gastric cancer were divided into two groups: the control group, and the neo - adjuvant chemotherapy group. All of the cases were performed gastrectomy. The neo - adjuvant chemotherapy group were given FOLFOX6 before operation. Incidence rates of anastomotic leak were compared between neo - adjuvant chemotherapy group and control group. Results There was no statistic difference of generation rate of anastomotic leak between control group and neo - adjuvant chemotherapy group ( P 〉 0.05 ). Conclusion The rate of anastomotic leak in post gastrectomy was not increased after neo - adjuvant chemotherapy.
机构地区 河南省肿瘤医院
出处 《医药论坛杂志》 2010年第18期47-48,共2页 Journal of Medical Forum
关键词 胃癌 新辅助化疗 吻合口瘘 Gastric cancer Neo- adjuvant chemotherapy Anastomotic leak
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