摘要
本文主要考察了基础培养基添加豆油以及不同发酵时间流加豆油对头孢菌素C发酵特性的影响。实验结果表明在72h,84h,96h三个时间添加点中,以72h添加豆油为最佳;72h的豆油添加中以0.8%的添加量效果最好,其脂肪酶活比对照平均高出14.8%,放瓶效价提高6.6%。为以后进行的发酵罐实验提供了有参考价值的数据。
The effect of adding soybean oil to basal culture medium and feed oil timing on cephalosporin C fermentation characteristics were studied. The results showed that among the three feeding points （72h, 84h and 96h）, 72h is the best one. It was showed that 0. 8% soybean oil feeding at 72h could increase lipase activity by 14. 8% and titer 6.6% respectively, compared to control. The results provide significant reference data for future bioreactor experiments.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
2010年第10期747-750,共4页
Chinese Journal of Antibiotics
关键词
豆油
头孢菌素C
脂肪酶
发酵
Soybean oil
Cephalosporin C
Lipase
Fermentation
