摘要
目的:通过文献检索和临床评价,观察羟基磷灰石义眼台材料特征及其在植入重建眼窝中的应用效果。方法:以用计算机检索维普数据库(http://www.cqvip.com/)及Pubmed数据库(http://www.ncbinlm.nih.gov/PubMed),选择主题内容与眼窝凹陷,施行眶内植入物重建眼窝关系密切的文章,排除基础研究类文章与重复性研究,结合文献对沈阳市第四人民医院眼科采用羟基磷灰石义眼台植入重建眼窝的47例(47只眼)进行归纳总结。结果:根据病眼不同条件,行一期植入29例,二期植入18例。经10～12个月随访,一期植入无明显并发症,二期植入出现4例并发症,其中结膜切口裂开2例,1例自行愈合,1例手术修补愈合,下穹窿变浅1例,行下穹窿修复术后得到矫正;义眼台暴露1例,经异体巩膜复盖修补结膜后愈合。其余均I期愈合,无感染,无交叉性眼炎发生,眼窝饱满,义眼台动感好,整形效果满意。结论:羟基磷灰石义眼台组织相容性好,无毒性,无抗原性,是矫治眼球摘除或眼内容物剜除术后眼窝凹陷及改善义眼活动度较好的办法。但因其材料的生物学因素仍存在一些并发症,主要有义眼台暴露、位置异常、感染以及结膜切口裂开、下穹窿变浅等。
OBJECTIVE：To observe material characteristics of hydroxyapatite orbital implant and the application in orbital reconstruction through the literature search and clinical evaluation.METHODS：VIP database （http：//www.cqvip.com/） and Pubmed database （http：//www.ncbinlm.nih.gov/PubMed） were searched on computer for articles related with sunken eye and orbital reconstruction by orbital implants,basic research articles and repetitive research were excluded,47 patients （47 eyes） underwent hydroxyapatite orbital implants for reconstruction at Department of Ophthalmology,the Fourth People＇s Hospital of Shenyang,were summarized.RESULTS：According to different conditions of affected eyes,29 cases received one-stage implants and 18 received second-stage implants.After 10-12 months of follow-up,no obvious complications of one-stage implantation was observed,while four cases appeared complications after secondary implantation,including conjunctival incision dehiscence in 2 cases,self-healing in 1 case,healing by surgical repair in 1 case,shallow lower fornix in 1 case,who was corrected after surgical repair;implant exposure in 1 case,who was healed by conjunctival patch covered by the sclera.The rest patients healed at one stage,with no infection or no occurrence of cross-ophthalmia,full eye socket,good dynamic of artificial eye,plastic results were satisfactory.CONCLUSION：Hydroxyapatite orbital implant with good histocompatibility,no toxicity or no antigenicity,is an effective approach to treat sudden eye and to improve the orbital activity following enucleation or evisceration of eye.Biological factors of the materials still have some complications,mainly implant exposure,abnormal location,infection and conjunctival incision dehiscence,and shallow lower fornix.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2010年第38期7197-7200,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
