摘要
目的探讨改善微循环对创伤性鼓膜穿孔愈合率及愈合时间的影响。方法 120例创伤性鼓膜中等穿孔患者按接诊时间顺序分为A、B、C、D四组:A组不作任何处理,B组口服复方丹参片,C组单纯明胶海绵贴补处理;D组明胶海绵贴补处理+静脉滴注复方丹参注射液。1～2周时分别评估四组鼓膜充血程度,1月时比较四组鼓膜穿孔愈合率及愈合时间。结果 1周及2周时A、B两组及C、D两组鼓膜充血评分差异无显著性(P>0.01),1月时A、B、C、D四组穿孔愈合例数及愈合率分别为20(71.43%)、17(73.91%)、25(92.59%)和24(96.00%),愈合时间分别为(27±2.3)d、(25±1.9)d、(16±2.6)d和(15±2.1)d,A、B两组及C、D两组穿孔愈合率及愈合时间差异无显著性(P>0.01)。结论应用改善微循环药并不能明显提高创伤性鼓膜穿孔愈合率,缩短穿孔愈合时间。
Objective To study effects on treatment outcomes in traumatic tympanic membrane perforation by microcirculation improvement. Methods One hundred twenty cases of traumatic tympanic membrane perforation were randomly selected to be observed （A）, treated with Compound Salvia （B）, patched with therapeutic gelatin sponge （C）, or treated with a combination of therapic gelatin sponge and intravenous Compound Salvia injection （D）. Circulation of the tympanic membrane was visually evaluated at 1-2 weeks and healing of the tympanic membrane was assessed at 1 month. Results Tympanic membrane circulation was not significantly different between A and B or between C and D （P 0.01） at 1-2 weeks. The healing rate was 71.43%, 73.91%, 92.59% and 96.00% and the average healing time was 27 ± 2.3 days, 25 ± 1.9 days, 16 ± 2.6 days and 15 ± 2.1 days at one month for the four treatment groups, respectively. These were not significantly different between A and B or between C and D. Conclusion Intravenous driping of microcirculation improving agents does not seem to improve the healing rate or shorten the healing time in treating traumatic perforation of the tympanic membrane.
出处
《中华耳科学杂志》
CSCD
2010年第3期296-298,共3页
Chinese Journal of Otology
基金
2009年浙江省一般科技计划项目(项目编号2009C33097)
关键词
鼓膜穿孔
外伤性
贴片
Tympanic membrane perforation
Traumatic
Patch
