摘要
目的研究丹参酮ⅡA对2型糖尿病肾血管病变炎症因子的干预作用和早期的治疗效果。方法将我院2型糖尿病肾血管病变病人72例随机分为基础组和治疗组,另选糖尿病未合并肾血管病变者36例为非治疗组。观察患者24hUAER、血清P-选择素、CRP、TNF-a、IL-6等的变化情况。结果治疗组的UAER在治疗后较治疗前显著的下降(P<0.05),糖尿病合并肾血管病变者炎症因子血清P-选择素、CRP、TNF-a、IL-6明显高于非治疗组。结论使用丹参素治疗早期的2型糖尿病肾血管病变具有一定的疗效,并能够明显减低炎症因子的发生。
Objective To study the tanshinone Ⅱ A on type Ⅱ diabetic renal vascular lesions the role of inflammatory factors and early intervention treatment.Methods Hospital Ⅱ diabetic patients with renal vascular disease 72 patients were randomly divided into two basic groups and the treatment group,elect diabetes not associated with renal vascular lesions were 36 cases of non-treatment group.Patients were observed 24h UAER,serum P-selectin,CRP,TNF-a,IL-6 and other changes.Results UAER treatment group after treatment than before treatment significantly decreased（P0.05）,diabetes with renal vascular lesions,inflammatory serum P-selectin,CRP,TNF-a,IL-6 was significantly higher than non-treatment group.Conclusion Early treatment Danshensu Ⅱ diabetic renal disease has some effect,and can significantly reduce the incidence of inflammatory cytokines.
出处
《中外医疗》
2010年第26期11-11,13,共2页
China & Foreign Medical Treatment
关键词
糖尿病
血管病变
炎症因子
丹参酮Ⅱ
A
Diabetes
Vascular disease
Inflammatory factors
Tanshinone Ⅱ A
