摘要
目的探讨妊娠相关性血小板减少症(pregnancy associated thrombocytopenia,PAT)的临床特征及其处理方法。方法回顾性分析39例PAT孕妇的临床表现,血小板参数,分娩方式与出血量的关系。结果 39例PAT孕妇84.6%(33/39)属于轻度血小板减少[血小板计数(50-99)×109/L],患病组剖宫产术或经阴道分娩两种分娩方式的产后出血量差异无统计学意义。与正常妊娠妇女相比,PAT组,血浆凝血致活酶(plasma thromboplastin,PT)、活化部分凝血激酶时间(activated partial thromboplastin time,APTT)、平均血小板体积(mean platelet volume,MPV)、血小板分布宽度(platelet distribution width,PDW)变化差异无统计学意义(P〉0.05)。结论 PAT大多数为轻度血小板减少,血小板功能正常、不增加产后出血的发生率,但若血小板计数〈20×109/L,应输注单采血小板并采取剖宫产分娩。
Objective To study the clinical features and threatment of pregnancy associated thrombocytopenia(PAT).Methods The relationship between the clinical manifestation,the platelet parameters,different deliveries and the hemorrhage volume in 39 cases with PAT was retrospectively analysis.Results Thirty-three PAT cases(84.6%)had mild thrombocytopenia(Plt:50~99×109/L).The difference of postpartum hemorrhage volume between the vaginal delivery and cesarean section was no significant(P0.05).The parameter of the thromboplastin(PT),activated partial thromboplastin time(APTT),mean platelet volume(MPV),platelet distribution width(PDW)in PAT group and that in control group was no significant difference(P0.05).Conclusion More of the PAT cases were the normal function of the platelet,less sum of the platelet without rising the incidence rate of postpartum hemorrhage does not rise.If the sum of the platelet was less than 20×109/L,single donor platelets transfusion is needed and cesarean section is the first choice for delivery.
出处
《中国计划生育和妇产科》
2010年第5期29-31,共3页
Chinese Journal of Family Planning & Gynecotokology
关键词
妊娠相关性血小板减少症
出血
剖宫产
自然分娩
pregnancy associated thrombocytopenia
hemorrhage
vaginal delivery
cesarean section