摘要
目的:回顾性分析本院输血患者血型不规则抗体的检出情况,探讨输血前不规则抗体筛查的重要性和高危科室。方法:微柱凝胶法和聚凝胺法对需要输血的2500例患者血清进行不规则抗体筛检。结果:2500例申请输血的患者不规则抗体总阳性率为1.0%;微柱凝胶检出的敏感度为100%,聚凝胺法敏感度为88.0%,2种方法的敏感度差异具有统计学意义(P<0.05)。肝病科、肛肠科以及肾病科不规则抗体检出阳性率占了总阳性率的80.0%。结论:微柱凝胶法进行输血前不规则抗体的筛检敏感度高,更有利于保证临床上的输血安全;对于肝病科、肛肠科以及肾病科等出现反复输血的科室,在输血前更应该进行不规则抗体的筛查,以减少输血风险。
Objective：To investigate the importance of irregular antibody screening before blood transfusion and high-risk departments. Method：Irregular antibodies of 2500 patients were detected by microcolumn gel test and polybrene method. Result：The total positive rate of irregular antibodies of 2500 blood transfusion cases was 1.0%. Sensitivities of microcolumn gel test and polybrene method were 100% and 88.0%,respectively. The sensitivity difference between this two methods had statistical significance （P0.05）. The irregular antibody positive rate of patients in department of liver disease,anal and rectal disease and nephrology were 80.0%. Conclusion：Irregular antibody screening by microcolumn gel test before blood transfusion could be more sensitive to ensure clinical safe blood transfusion; for department of liver disease,anal and rectal disease and nephrology occuring repeated blood transfusions,irregular antibody screening before transfusion should be paid more attention to reduce blood transfusion risk.
出处
《临床血液学杂志（输血与检验）》
CAS
2010年第4期464-466,共3页
Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)
关键词
不规则抗体
微柱凝胶法
输血安全
交叉配血
irregular antibodies
microcolumn gel
blood transfusion safety
cross matching
