摘要
目的:了解衢州市健康儿童口咽部流感嗜血杆菌(Hi)携带率、菌型特点及对常用抗生素的耐药情况,提供Hi感染的临床防治依据。方法:选择衢州一乡镇幼儿园健康儿童70名,进行口咽部Hi携带率监测,Hi分离株进一步作生物学分型及耐药性研究。结果:从70份样品中分离到流感嗜血杆菌12株,阳性率为17.14%,生物学分型分别为Ⅱ型8株,Ⅲ型4株;血清分型为Hia、Hif血清型各1株,其他10株为不可分型株(NTHi),Hi分离株对临床常用抗生素耐药程度不高,仅复方新诺明耐药率稍高,为66.7%。结论:衢州市健康儿童Hi带菌以不可分型株为主,对常见抗生素耐药情况不严重,对环丙沙星、头孢噻肟、头孢曲松、阿奇霉素、利福平、阿莫西林克拉维酸、头孢呋新钠有较高的敏感性。
Objective：To understand the status of oral pharyngeal carrying rate of Haemophilus influenza in healthy children in Quzhou and find out the type distribution and susceptibility of Hi,thus providing data for Hi-associated diseases prevention and cure.Methods： Seventy children in the kindergarten of one town in Quzhou were surveyed,and the carrying rates of Haemophilus influenza were studied.All Haemophilus influenza strains were biologically differentiated and their resistance to antibiotics were tested.Results： 12 Haemophilus influenza strains were isolated from 70 samples with a positive rate of 17.14%.Biology II and III were 9 and 3 strains.Serotype Hia and Hif was one strain respectively and others were non-typable Hi（NTHi） strains.Hi isolates were poor resistance to most antibiotics with exception of sulpham ethoxazole / trim ethop rim（the resistance rate： 66.7%）.Conclusion： The main serotype of Hi in healthy children in Quzhou was non-typable Hi（NTHi） strains and Haemophilus influenza was susceptible to Ciprofloxacin,cefotaxime,Ceftriaxone,azithromycin,rifampicin,Amoxicillin-clavulanic acid and Cefuroxime sodium.
出处
《中国卫生检验杂志》
CAS
2010年第10期2583-2584,共2页
Chinese Journal of Health Laboratory Technology
关键词
流感嗜血杆菌
带菌调查
分型
Haemophilus influenza
Carriage survey
Typing
