摘要
讨论了药物引起肝脏毒性作用的生物标识及肝脏毒性研究方法;包括血清酶学改变、肝脏排泄功能、肝脏化学组分改变、肝损害与修复、肝细胞凋亡、体外肝损害评价等等。
The review is discussion on biomarker of drug-induced hepatotoxicity and research method of hepatotoxicity,included alternation of serum enzymology,hepatic excretion function,alternation of hepatic biochemical constitution,injure and repaire,hepatic cell apoptosis,in vitro hepatic cell damage evaluation et al.
出处
《药物分析杂志》
CAS
CSCD
北大核心
2010年第10期1981-1984,共4页
Chinese Journal of Pharmaceutical Analysis
关键词
动物
肝损伤
肝细胞酶
肝损伤检测
animal
hepatotoxicity
hepatic cellular enzyme
hepatotoxicity detection
