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乌司他丁治疗急性胰腺炎的临床疗效观察 被引量:13

Therapeutic effects on acute pancreatit of domestically manufactured ulinastatin
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摘要 目的:探讨乌司他丁治疗急性胰腺炎的临床疗效。方法:将62例急性胰腺炎患者随机分为观察组和对照组,分别在常规治疗基础上加予乌司他丁或奥曲肽,根据病情轻重予以不同治疗方案,比较两组患者的疗效差异。结果:两组患者在临床症状消失天数、血淀粉酶恢复天数、尿淀粉酶恢复天数、白细胞计数恢复天数、治愈率及总有效率等方面差异无统计学意义(P〉0.05),两组患者不良反应发生情况差异无统计学意义(P〉0.05)。结论:乌司他丁治疗急性胰腺炎疗效确切,不良反应小,可在临床推广使用。 Objective:To investigate the therapeutic effects of domestically manufactured ulinastatin on acute pancreatitis and explore its mechanism.Methods:A total of 256 patients with acute edematic pancreatitis were randomized into the treated group and control group,the changes in symptoms,physical signs andlaboratory data were observed.Result:In the control group,30 patients were treated with sandostatin,the effective rate was 86.7% in light type,90.0% in severe type.While in the treated group,32 patients were treated with ulinastatin,the effeative rate was 84.3% in light type,80.0% in severe type.There was no significant difference between the treated group andcontrol group (P0.05).Conclusion:Ulinastatin is an effective and safe agent for treatment of acute pancreatitis,and with great value to promote.
作者 李小燕
出处 《药物分析杂志》 CAS CSCD 北大核心 2010年第10期1963-1965,共3页 Chinese Journal of Pharmaceutical Analysis
关键词 乌司他丁 急性胰腺炎 疗效 ulillastatln acute pencreatitis curative effect
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