期刊文献+

恶性腹膜间皮瘤15例诊治体会 被引量:5

Experience of diagnosis and treatment for 15 cases of malignant peritoneum mesothelioma
原文传递
导出
摘要 为了探讨恶性腹膜间皮细胞瘤患者的临床特点、诊治方法以及预后,回顾性分析我院诊治的恶性腹膜间皮瘤患者15例的人口学资料、临床表现、影像学特点、腹腔镜下表现以及治疗后转归。患者主要临床表现为乏力13例(86.7%),腹胀12例(80.0%),腹痛11例(73.3%),腹部不适10例(66.7%),消瘦、贫血6例(40%),腹水13例(86.7%),腹部膨隆13例(86.7%),腹部包块6例(40.0%)。腹部超声和CT检查对该病的诊断没有特异性。腹腔镜下表现为粉红色结节、腹膜广泛或局部胼胝样增厚或局部包块。腹膜表面尚存在不同程度充血、水肿及血管扩张。生存期3~18个月,平均9个月。初步研究结果提示,恶性腹膜间皮瘤临床特征性少,恶性程度大,常规检查难以确诊,腹腔镜在诊断方面具有优势,而且安全可行。 The objective of this study was to investigate the clinical characteristics,prognosis and diagnostic methods of malignant peritoneum mesothelioma. The demographic data,clinic features,imaging features,manifestations with laparoscope,and prognosis of 15 cases of pathologically proved malignant peritoneum mesothelioma were analyzed. The common clinical manefestations were hypodynamia (86.7%,13 cases) ventral bloating(80.0%,12 cases),abdominal pain with emaciation (73.3%,11 cases),abdominal discomfort (66.7%,10 cases) peritoneal fluid (86.7%,13 cases),abdominal distention (86.7%,13 cases),abdominal mass(40.0%,6 cases),and anemia(40%,6 cases),etc. There was no specificity in diagnosing with abdominal ultrasoud. Under laparoscopy,pink nodules,diffusing or local peritoneal thickening of callus-like,or local mass were found on the peritoneum. Hyperemia,edema and vasodilatation could be seen on peritoneal surface. The survival time in this group averaged 9 months (3-18 months). Malignant peritoneal mesothelioma is highly malignant disease without distinct clinical features. It is difficult to diagnose this disease at present under routine clinical situation. Laparoscopy has an advantage in the diagnosis with securrty.
机构地区 临安市人民医院
出处 《中华肿瘤防治杂志》 CAS 2010年第17期1381-1382,共2页 Chinese Journal of Cancer Prevention and Treatment
关键词 间皮瘤 腹膜 腹腔镜 诊断 治疗 mesothelioma peritoneum laparoscopes diagnosis therapy
  • 相关文献

参考文献11

二级参考文献15

  • 1温加登,史密斯,贝内特,著.西氏内科学(第2卷).第19版.北京:世界图书出版公司,1995.184~186.
  • 2Kim N W,Platyszek M A,Prowse K R,et al.Specific association of human telomerase activity with immortal cell and cancer[J].Science,1994,266 (5193):2011-2015.
  • 3Cardozon P L.A critical evaluation of 3000 cytologic analysis of pleural fluid,ascitic fluid and pericardial fluid[J].Acta Cytol,1996,10(4):455-460
  • 4Dekker A,Bupp P A.cytology of serous effusions:an investication into the usefulness of cell blocks versus smears[J].Am J Clin Pathol,1978,70(6):855-860.
  • 5Schofield K P,Aqaila T,Rimm D L,et al.The cell adhesion molecule.E-cadherin,distinguishes mesothelial cells from carcinoma cells in fluids[J].Cancer,1997,81(5):293-298.
  • 6Morin G B.The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeates[J].Cell,1989,59(3):521-529.
  • 7Counter C M,Hirte H W,Bacchetti S,et al.Telomerase activity in human ovarian carcinoma[J].Proc Acad Sci U S A,1994,91 (8):2900-2904.
  • 8Zheng P S,Iwasaka T,Yamasaki F,et al.Telomerase activity in gynecologic tumors[J].Gynecol Oncol,1997,64 (1):171 -175.
  • 9Hess J L,Highsmith W E D.Telomerase detection in body fluids[J].Clin Chem,2002,48(1):18-24.
  • 10Piazza D,Caruso F,Scaringi S,et al.Primary diffuse malignant peritoneal mesothelioma:case report and update of therapy[J].J Surg Oncoe,2000,75(1):55.

共引文献14

同被引文献59

引证文献5

二级引证文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部