摘要
目的探讨角膜清创联合羊膜移植羊膜覆盖治疗真菌性角膜炎的手术适应证的选择和临床效果。方法2008年3月至2009年11月就诊的17例真菌性角膜炎患者，视力为FC／50cm～0．2，经角膜刮片法10％KOH溶液处理后查见菌丝，常规全身、局部抗真菌治疗3周至2个月后，患者病情迁延不愈，角膜涂片仍见菌丝。手术适应证为感染深度小于1／3角膜厚度，感染范围小于1／3角膜面积。手术方式：在局麻下行角膜清创，至角膜植床无明显感染迹象。溃疡面行羊膜小植片移植，角膜表面行羊膜大植片覆盖。术后结膜下注射0．2％氟康唑注射液0．5ml。结果16例患者术后视力为0．5～1．0，感染得到控制。羊膜小植片与角膜融合，可见角膜组织内云翳形成。1例患者术后感染灶融解，改行板层角膜移植术后治愈。结论角膜清创联合羊膜移植羊膜覆盖可以有效治疗药物难以治愈的表浅真菌性角膜炎。良好的手术适应证的选择不仅可以治愈真菌性角膜炎，而且可以获得良好的术后视力。真菌复发和角膜融解是手术后的危险因素。
Objective To evaluate the efficiency ofamniotic membrane transplantation and amniotic membrane cover for fungal keratitis. Methods Amniotic membrane transplantation and amniotic membrane cover was done on 17 cases of fungal keratitis after infected tissue had been completely cleared in our hospital from March 2008 to November 2009. Results Amniotic membrane graft grown well. Sixteen cases of fungal keratitis were cured and visual acuity were 0.5-1.0, and one recurring case was performed lamellar keratoplasty and visual acuity was 0.2. Conclusions Amniotic membrane transplantation and amrdotic membrane cover is an effective method for fungal keratitis.
出处
《中国实用眼科杂志》
CSCD
北大核心
2010年第9期992-994,共3页
Chinese Journal of Practical Ophthalmology
关键词
角膜炎
真菌
羊膜
Fungal keratitis
Amniotic membrane transplantation
Amniotic membrane cover
