摘要
目的探讨影响骨肉瘤生存期的相关临床因素。方法统计42例骨肉瘤患者的年龄、性别、病程、碱性磷酸酶(AKP)、乳酸脱氢酶(LDH)、肿瘤分级、肿瘤部位、肿瘤体积以及是否保肢等临床资料,分析这些临床特征与生存期之间的关系。结果 3年生存率22.7%;单因素分析中病程、乳酸脱氢酶、肿瘤体积、是否保肢4个因素无统计学意义,年龄、性别、碱性磷酸酶、肿瘤分级及肿瘤部位5个因素具有统计学意义;多因素分析中仅肿瘤分级具有统计学意义。结论年龄、性别、碱性磷酸酶、肿瘤分级及肿瘤部位5个因素,尤其是肿瘤分级对骨肉瘤患者生存时间起着重要的影响。
Objective To explore the clinical factors that effected the survival time of patients with osteosarcoma.Methods Collecting the clinical data of 42 cases with osteosarcoma,induding age,gender,course of disease,AKP,LDH,staging,disposition,capacity and modus operandi.The correlation between these clinical characteristics and survival time were studied.Results The 3-year survival rate of the total group was 22.7%.The difference in four factors-course of disease,LDH,capacity and modus operandi-were not significant,and the difference in five factors-age,gender,AKP,staging and disposition-were significant in monovariate analysis.However,only the difference of staging was significant in multivariate analysis.Conclusion Age,gender,AKP,staging and disposition,especially to staging,are influencing factors of survival time in osteosarcoma.
出处
《中国实用医药》
2010年第28期84-86,共3页
China Practical Medicine
关键词
骨肉瘤
预后
生存期
Osteosarcoma
Prognosis
Survival time
