摘要
目的现场观察青蒿琥酯预防血吸虫病的效果。方法对1998年长江抗洪抢险接触疫水的人民解放军、武警部队官兵和机关干部服用青蒿琥酯，并以未服用青蒿琥酯预防，而用吡喹酮早期治疗者作对照。结果调查12233人，无1例罹患急性血吸虫病；3个月后考核，粪检阳性率为0．22％；血检（COPT、IHA双项）阳性率为7．28％。而紧急赴嘉鱼牌州湾抢险的解放军某部，只用吡喹酮早期治疗，该部2038名官兵中，粪检阳性率为8．15％，血检阳性率为13．24％，其感染率明显高于服用青蒿琥酯的抗洪人员。结论大规模应用青蒿晓酯预防血吸虫病，尤其对预防血吸虫急性感染具有显著的作用。
Objective To observe the effect of artesunate to prevent schistosomiasis in the field' Methods 12 233 people (PLA men,police men and of ficers) who contacted with the infested water during fighting flood in 1998 took artesunate, and 2038 people did not take artesunate but treated with praziquantel as control. Results No one had acute schistosomiasis arnong those people who took artesunate. The stool positive rate was 0. 22 %, and the sero-diagnosis (COPT, IHA) positive rate was 7. 28 % after taking artesunate 3 months. However, among those people who did not take artesunate but took praziquantel,the stool positive rate was 8. 15 %,and the sero-diagnosis positive rate was 13. 24 %. The infection rate was much higher in the latter. Conclusion It played a significant role to use artesunate on large-scale to prevent schistosomiasis,especially acute schistosomiasis.
出处
《中国血吸虫病防治杂志》
CAS
CSCD
1999年第3期143-145,共3页
Chinese Journal of Schistosomiasis Control
关键词
青蒿琥酯
血吸虫病
预防
长江
抗洪
Artesunate, Schistosomiasis, Prevention, The Yangtze River, Flood
