摘要
目的观察无保护左主干病变,应用药物洗脱支架介入治疗后冠状动脉造影随访结果,并分析其影响因素。方法选择无保护左主干病变患者150例,其中48例在平均(10.0±7.5)个月进行了冠状动脉造影复查,根据冠状动脉造影显示有无狭窄分为:再狭窄组12例和无再狭窄组36例。结果与无再狭窄组比较,再狭窄组患者随访时最小管腔直径明显减小[(2.7±1.0)mm vs (3.5±0.4)mm,P=0.0001]、直径狭窄率明显升高[(31.4±26.4)% vs (8.3±5.3)%,P=0.0000]、晚期管腔丢失明显升高[(0.8±0.7)mm vs (0.2±0.3)mm,P=0.0000];双支架置入术的再狭窄率明显高于单支架置入术[(75.0% vs 13.9%),P=0.0011]。结论左主干远端分叉病变双支架置入术的疗效较差,冠状动脉旁路移植术应作为首选。
Objective To analyse the influencing factors for restenosis of unprotected left main coronary artery after intervention with drug-eluting stents. Methods From April 2003 to June 2008, 150 patients underwent unprotected left main coronary artery stenting. Of them, 48 （32%） were reviewed by coronary angiography after（10.0±7.5） months. Results By comparing restenosis group with non-restenosis group in the follow-up angiographical results, the minimal lumen diam- eters were（2.7±1.0） mmvs （3.5±0.4） mm, P = 0.0001,the rates of stenosis were（31.4±26.4）% vs （8.3±5.3）%, P = 0. 0000,late lumen loss was（0.8±0.7） mm vs （0.2±0.3） mm, P = 0.0000 and stenting technique in the two groups was different significantly. Restenosis rate of the two-stent technique was greater than that of one-stent technique（75.0% vs 13.9%, P = 0. 0011）. Conclusion The therapeutic efficacy of two-stents implantation for left main coronary artery distal-bifurcation lesion is unsatisfactory and coronary artery bypass grafting should be the first choice.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2010年第9期795-798,共4页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
