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异丙酚和异氟醚麻醉对老年患者术后认知功能的影响 被引量:10

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摘要 目的探讨异丙酚和异氟醚麻醉对老年患者术后认知功能的影响。方法选择骨科全麻手术患者40例,术前无神经精神系统疾病史,近1个月未服用脑血管扩张药,ASAⅠ~Ⅱ级。随机分为2组:Ⅰ组为异丙酚组(n=20),Ⅱ组为异氟醚组(n=20),术中分别以异丙酚和异氟醚维持麻醉。用简易智能量表(MMS)的方法评估两者对认知功能的影响。结果 2组麻醉时间及术中各时点MAP、HR、SpO_2比较差异均无统计学意义(P<0.05)。MMS评分:Ⅱ组在麻醉结束后6 h(T_5)、12 h(T_6)、24 h(T_7)时,Ⅰ组在T_5、T_6时较麻醉诱导前(T_0)明显降低,Ⅱ组T_7时点与Ⅰ组同时点比较差异有统计学意义(P<0.05)。结论异氟醚和异丙酚用于老年患者麻醉均能引起术后认知功能障碍,但异丙酚麻醉术后认知功能障碍恢复明显快于异氟醚麻醉患者。
出处 《疑难病杂志》 CAS 2010年第10期773-774,共2页 Chinese Journal of Difficult and Complicated Cases
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参考文献14

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