摘要
目的探讨结核分枝杆菌(TB)、乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)等混合感染对艾滋病患者高效抗反转录病毒治疗(HAART)后CD4的影响,以提高艾滋病合并混合感染的诊断治疗水平。方法对43例HIV/TB、11例HIV/TB/HBV、11例HIV/TB/HCV、5例HIV/TB/HBV/HCV及44例HIV患者,进行HAART,比较治疗前、后的CD4计数的变化;比较治疗后不同时间CD4增加值的变化情况。结果经HAART后各感染组CD4计数不同程度增加,呈向上趋势,治疗后的第6个月CD4达到相对高值,并可维持12个月;治疗后12个月比3、9个月治疗效果更好;各感染组之间CD4计数变化情况无差别。结论各感染组患者经HAART后,CD4计数都有不同程度增加,但各组间之间的差别不大。
Objective To evaluate the influence of tuberculosis（TB）,hepatitis B virus（HBV）,hepatitis C virus（HCV）and HIV co-infection on the CD4 count after highly active anti-retroviral therapy（HAART）,enhance the diagnosis and treatment of AIDS of mixed infection.MethodsThe CD4＋T lymphocytes of 43 cases HIV/TB,11 cases HIV/TB/HBV,11 cases HIV/TB/HCV,5 cases HIV/TB/HBV/HCV and 44 cases of HIV patients at different time points after HAART were detected and compared.ResultsThe CD4 count increased after HAART in different degrees,showing an increasing tendency,CD4 count achieved a relatively high value 6 months after treatment,and maintained about 12 months.Compared with treatment after 3,9 months,the effect at 12 months was much better;no difference the changes of CD4 count was among different groups.ConclusionThe CD4 count of infected patients increased in different degrees,however,the difference was not significant.
出处
《广西医学》
CAS
2010年第10期1167-1169,共3页
Guangxi Medical Journal
基金
全球基金中国艾滋病项目(CHN-304-G03-H)
广西南宁市科学研究与技术开发计划项目(200901014C)
关键词
艾滋病
结核病
乙型肝炎
丙型肝炎
CD4
Acquired immune deficiency syndrome
Tuberculosis
Hepatitis B
Hepatitis C
CD4＋T lymphocytes
