摘要
目的分析ICU爆发12例PDR-AB菌株的抗生素耐药性、同源性及临床情况。方法应用K-B法进行抗菌药物敏感性试验,REP-PCR法检测11株PDR-AB同源性,统计患者合并感染、使用碳青霉烯情况、预后等情况。结果 12株PDR-AB仅50.00%对米诺环素敏感、中介33.33%,头胞哌酮/舒巴坦中介50.00%,氨苄西林/舒巴坦中介16.67%。11株PDR-AB同源10株。患者50%合并其他细菌感染、16.7%合并真菌感染,100%使用过碳青霉烯,病死率58.3%。结论 ICU爆发PDR-AB菌株仅50.00%对米诺环素敏感,绝大部分为同源株,多合并其他微生物感染,病死率高。
Objective To investigate the drug resistance,homology and clinical features of 12 strains PDR-AB outbreak in ICU.Methods Antimicrobial susceptibility tested by K-B method,REP-PCR was carried out to detect their homology.Analysis of clinical features such as complicated infection,carbapenems applied and prognosis.Results 50.00% of 12 strains PDR-AB sensitive to Minocycline,33.33% intermediate sensitive to Minocycline,50.00% intermediate sensitive to Cefoperazone/Sulbactam,16.67% intermediate sensitive to Ampicillin/Sulbactam;50% complicated with bacterial infection and 16.7% complicated with fungi infection,all patients applied carbapenems,mortality rate was 58.33%.Conclusions The PDR-AB strains outbreak in ICU,only 50.00% were sensitive to Minocycline,most of them were homogenous,and complicated with other micro-organism infections;patient＇s mortality was high.
出处
《慢性病学杂志》
2010年第10期1179-1181,共3页
Chronic Pathematology Journal
关键词
不动杆菌感染
鲍氏不动杆菌
重症监护病房
Acinetobacter Infections
Acinetobacter baumannii
Intensive Care Units
