摘要
目的：比较硬膜外一次性注射吗啡、曲马多或痛力克用于术后镇痛的效果。方法：１５０例在硬膜外阻滞下行择期盆腔手术病人随机分为三组，分别应用吗啡１５ｍｇ、曲马多２５ｍｇ和痛力克３０ｍｇ在关腹后硬膜外注射。采用双盲法观察镇痛时间、疼痛缓解率及有关并发症。结果：吗啡组术后镇痛时间（２４±８１ｈ）显著长于曲马多（５１±１２ｈ）和痛力克（１０４±７５ｈ），但有恶心、呕吐、尿潴留及皮肤瘙痒等副作用。结论：曲马多或痛力克虽然镇痛时间短于吗啡，但副作用少，且无延迟性呼吸抑制之虑。
Objective: The analgesic effect of morphine, tramadol and ketorolac was compared in adult pelvic surgical patients under epidural blockade. Methods: 150 patients were randomly divided into three groups. The duration of analgesia and the pain relief rate were investigated with double blind method after epidural injection of morphine 1 5mg, tramadol 25mg or ketorolac 30mg. Results: Analgesic duration of morphine was 24 0±8 1h, which was significantly longer than that of tramadol (5 1±1 2h) and ketorolac (10 4±7 5h). The incidence of nausea, vomiting and skin itch in morphine group was more than that in the other two groups. Conclusion: Epidural tramadol or ketorolac can be used for postoperative pain relief using repeated injection technic.
出处
《临床麻醉学杂志》
CAS
CSCD
1999年第2期83-84,共2页
Journal of Clinical Anesthesiology
