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基质碱金属蛋白酶（MMPs）与早产 被引量：1

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摘要 早产是指妊娠满28周至不足37周（196．258）之间终止者，目前，全球发病牢保持在10％左右。早产儿由于器官功能不成熟和免疫功能不完善，产生许多并发症而生存率低下，75％-80％的围生儿死亡和早产有关。近年来，对早产的研究颇多，但早产发生的原因和发病机制尚未完全明了。
作者 王海霞
机构地区 山东省日照市莒县人民医院妇产科
出处 《中国保健营养（临床医学学刊）》 2010年第8期117-119,共3页 China Health Care Nutrtion
关键词 早产儿 金属蛋白酶 基质 发病机制 围生儿死亡 免疫功能 器官功能 碱
分类号 R714.21 [医药卫生—妇产科学]
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参考文献16

  • 1Drazancic h. Antenatal care in developing countries-what should be done[J].J Perinat Med, 2001, 29 (3): 188.
  • 2Nagase H. Woessner JF JR. Matrix metalloproteinases[J].J Biol Chem, 1999, 274 (21): 21491-21494.
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  • 6刘新民,万小平,宋玉琴,等主译.现代妇产科疾病诊断与治疗[M].第8版.北京:人民卫生出版社,1998:10.
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  • 10王晗,董旭,葛常辉,朱正美.基质金属蛋白酶在生殖中的作用与调控[J].国外医学（计划生育分册）,2002,21(3):141-144. 被引量：6

二级参考文献22

  • 1高雨农.下生殖道感染与妊娠结局[J].国外医学（妇产科学分册）,1994,21(3):150-152. 被引量：6
  • 2Nagase H, Woessner JF Jr. Matrix metalloproteinases. J Biol Chem, 1999, 274(31): 21491-21494
  • 3Keller NR, Sierra-Rivera E, Eisenberg E, et al. Progesterone exposure prevents matrix metalloproteinase-3(MMP-3) stimulation by interlukin-1 alpha in human endometrial stromal cells. J Clin Endocrinol Metab, 2000, 85(4): 1611-1619
  • 4Zhang J, Hampton AL, Nie G, et al. Progesterone inhibits activation of latent matrix metalloproteinase(MMP)-2 by membrane-type MMP: enzymes coordinately expressed in human endometrium. Biol Reprod, 2000, 62(1): 85-94
  • 5Brew K, Dinakarpandian D, Nagase H. Tissue inhibitors of metalloproteinases evolution, structure and function. Biochim Biophys Acta, 2000, 1477(1-2): 267-283
  • 6Freitas S, Meduri G, Le Nestour E, et al. Expression of metalloproteinases and their inhibitors in blood vessels in human endometriurn. Biol Reprod, 1999, 61(4 ): 1070-1082
  • 7Curry TE Jr, Osteen KG. Cyclic changes in the matrix metalloproteinase system in the ovary and uterus. Biol Reprod, 2001, 64(5):1285-1296
  • 8Soini Y, Alarakkola E, Autio-Harmainen H. Expression of messenger RNAs for metalloproteinases 2 and 9, type Ⅳ collagen, and laminin in nonneoplastic and neoplastic endometrium. Hum Pathol, 1997, 28(2): 220-226
  • 9Nuttall RK, Kennedy TG. Epidermal growth factor and basic fibroblast growth factor increase the production of matrix metalloproteinases during in vitro desidualization of rat endometrial stromal cells. Endocrinology, 2000, 141(2):629-636
  • 10Reponen P, Leivo I, Sahlberg C, et al. 92-kDa type Ⅳ collagenase and TIMP-3, but not 72-kDa type Ⅳ collagenase or TIMP-1 or TIMP-2, are highly expressed during mouse embryo implantation. Dev Dyn, 1995, 202(4): 388-396

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中国保健营养（临床医学学刊）
2010年 第8期

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