摘要
A series of α-bromoarylethanones were prepared in high yields by a practical and efficient method. The arylethanones were reacted with bromine to give a mixture of α- and α, α-dibromides, which were debrominated with diethylphosphite in the presence of triethylamine to give the desired α-monobromo products.
本文报道了采用溴素进行羰基α-溴代反应而后经亚磷酸二乙酯和三乙胺脱溴反应制得羰基α-单溴代物的方法,该方法具有实用、收率高和易于工业化等优点。
