摘要
An unusual diterpenoid excoagallochaol A （1）, together with epi-β-amyrin （2）, epitaraxerol （3）, epi-a-amyrin （4）, epilupeol （5）, betulin （6）, betulinic acid （7）, lupenone （8）, betulone （9）, betulonic acid （10）, （9Z,12Z,15Z）-2,3-dihydroxypropyl octadecatrienoate （11）, and （9Z,12Z）-2,3-dihydroxypropyl octadecadienoate （12）were isolated from the stems of Excoecaria agallocha L. Their structures were elucidated by spectroscopic analyses, and the absolute stereochemistry of 1 was assigned using Mosher method. Compounds 4, 8, 10-12 were isolated from the genus Excoecaria for the first time.
采用多种色谱学方法和波谱学技术,从红树植物海漆Excoecaria agallocha L.中分离得到12个化合物,分别鉴定为excoagallochaol A(1),epi-β-amyrin(2),epitaraxerol(3),epi-α-amyrin(4),epilupeol(5),betulin(6),betulinic acid(7),lupenone(8),betulone(9),betulonic acid(10),(9Z,12Z,15Z)-2,3-dihydroxypropyl octadecatrienoate(11),(9Z,12Z)-2,3-dihydroxypropyl octadecadienoate(12),并应用改良Mosher法确定了二萜化合物1的绝对构型。化合物4,8,10-12为首次从大戟科海漆属中分得。
基金
National Key Innovation Project(Grant No.2009ZX- 09501-014,DYXM-115-02-2-09)
