摘要
流行病学证据显示：癌症发生率和糖尿病、某些糖尿病风险因子以及糖尿病治疗有关。由美国糖尿病协会（ADA）和美国癌症学会（ACS）汇集的专家共识，回顾了科学研究现状。包括：（1）糖尿病和癌症发生及预后的关系：（2）糖尿病和癌症共同的危险因子。（3）在糖尿病和癌症风险之间可能的生物学联系。（4）糖尿病的治疗是否影响癌症发生及预后。糖尿病和癌症都是常见病，严重影响着人类的健康。流行病学证据显示：糖尿病患者有发生多种癌症的较高风险；2型糖尿病（T2DM）和癌症有许多共同的危险因子。但目前T2DM和癌症之间的生物学联系尚未完全明了。而且，观察性研究的证据还显示：某些治疗高血糖的药物，增加或减少癌症发生的风险。鉴于此，ADA和ACS在2009年12月的研讨会上达成以下共识。
Epidemiologic evidence suggests that cancer incidence is associated with diabetes as well as certain diabetes risk factors and treatments. This consensus statement of experts assembled jointly by the American Diabetes Association and the American Cancer Society reviews the state of science concerning： （ 1 ） the association between diabetes and cancer incidence or prognosis. （2） risk factors common to both diabetes and cancer. （3） possible biologic links between diabetes and cancer risk. and （4） whether diabetes treatments influence the risk of cancer or cancer prognosis. Diabetes and cancer are common diseases that have a tremendous impact on health worldwide. Epidemiologic evidence suggests that people with diabetes are at a significantly higher risk of many forms of cancer. Type 2 diabetes and cancer share many risk factors, but to our knowledge,potential biologic links between two diseases are incompletely underslood. Moreover,evidence from obsmwational studies suggests that some medications used to treat hyperglycemia are associated with either an increased or reduced risk of cancer. Against this backdrop,the American Diabetes Association and the American Cancer Society convened a consensus development conference in December 2009.
出处
《国际内分泌代谢杂志》
2010年第5期353-358,共6页
International Journal of Endocrinology and Metabolism
关键词
糖尿病
癌症
美国糖尿病协会
美国癌症学会
Diabetes mellitus
Cancer
American Diabeles Association
American Cancer Society
