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新生儿脐血脂联素相关因素的研究进展

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摘要 脂联素(Adiponectin,APN)是近年来发现的一种由脂肪组织分泌的由244个氨基酸组成的蛋白质类激素,在血液中以二聚体、六聚体和多聚体(HWM)形式存在〔1,2〕,具有调节胰岛素敏感性、抗炎和抗动脉粥样硬化的重要作用。已发现两种脂联素受体在体内广泛分布,AdipoR1主要分布在骨骼肌,AdipoR2主要分布在肝脏。由于脂联素是调节胰岛素和糖代谢的关键因子,而胎儿的生长发育受胰岛素和糖代谢的影响,因此,脂联素可能是调节胎儿宫内发育的候选因子之一〔3〕。现就脐血脂联素相关因素的研究进展综述如下:
出处 《中国妇幼保健》 CAS 北大核心 2010年第28期4159-4161,共3页 Maternal and Child Health Care of China
基金 山东省教育厅2007年度科技计划项目(项目编号:J07WE23)
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