期刊文献+

急性心肌梗死PCI术前应用盐酸替罗非斑有效性与安全性评估

急性心肌梗死PCI术前应用盐酸替罗非斑有效性与安全性评估
暂未订购
导出
摘要 目的探讨急性心肌梗死PCI术前应用盐酸替罗非斑安全性。方法选本院102例急性心肌梗死行急诊PCI术前应用盐酸替罗非斑的病人,与98例术前不给盐酸替罗非斑仅行急诊PCI术作为对照组。术前均嚼服用阿司匹林片300mg;硫酸氢氯吡格雷片600mg;两组患者观察术中复流及出血事件。结果用盐酸替罗非斑的血管闭塞的较对照组明显少。结论早期应用盐酸替罗非斑可以改善复流,同时也增加出血事件,出血事件与用量有关。 Objective To investigate the acute myocardial infarction before the application of PCI Tirof iban Hydrochloride spot security.Methods 102 cases of hospital acute myocardial infarction before the application of emergency PCI Tirofiban Hydrochloride plaques of patients,78 cases with no preoperative Tirofi ban Hydrochloride spot emergent PCI patients only as a control group.Preoperative chewing aspirin tablets are 300mg;clopidogrel bisulfate tablets 600mg;were observed in patients with intraoperative flow and bleeding events.Conclusion Early Tirof iban Hydrochloride applications can improve the flow pattern,but also increased bleeding events,bleeding events have great relations with the dosage.
出处 《当代医学》 2010年第26期151-152,共2页 Contemporary Medicine
关键词 急性心肌梗死 出血事件 TIMIN 急诊PCI Acute myocardial infarction creatine phosphate kinase troponin T emergency PCI
  • 相关文献

参考文献7

  • 1YEH K H,CHEN M C,CHANG H W,et al.Effect of adjunctive tirofiban therapy on angiographic and clinical outcomes in patients with ST-segment elevated acute myocardial infarction undergoing primary stenting[J].Jpn Heart J,2004,45:31-41.
  • 2SMITH SC J P,,FELDMAN T E,HIRSHFELD JW,et al.ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention:a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to Update 2001 Guidelines for Percutaneous Coronary Intervention)[J].Circulation,2006,113:166-286.
  • 3宋玉娥,王琳,李芳,龚培力,王朝晖,党瑜华.盐酸替罗非班对急性冠状动脉综合征的疗效和安全性评价[J].临床心血管病杂志,2006,22(4):220-222. 被引量:71
  • 4WARNHOLTZ A,OSTAD M A,HEITZEP,T,et al.Effect of tirofiban on percutaneous coronary inter-vention-induced endothelial dysfunction in patients with stable coronary artery disease[J].Am J Cardiol,2005,95,20-23.
  • 5Elis SG,Tendera M,de Belder MA,et al.Facilitated PCI in patients with ST-elevation myocardial infarction[J].N Engl J Med,2008,358,2205-2217.
  • 6ASSENT-4 POI Investigatiors.Primay versus tenecteplase-facilitated percutaneous coronary interventions in patients with ST-segment elevation acute myocardial infarction:randomized trial[J].Lancet,2006,367:569-578.
  • 7De Luca G,Suryapranata H,OTTervanger JP,et al.Time delay to treatment and mortality in primary angioplasty for acute myocardial infarction:every minute of delay counts[J].Circulation,2004,109:1806-1808.

二级参考文献7

  • 1STONE G W, MOLITERNO D J, BERTRAND M,et al. Impact of clinical syndrome acuity on the differential response to 2 glycoprotein Ⅱb/Ⅲa in hibitors inpatients undergoing coronary stenting the TARGET trial[J]. Circulation, 2002,105 :2345- 2354.
  • 2CROUCH M A, NAPPI J M, CHEANG K I. Glycoprotein Ⅱb/Ⅲa receptor inbibitors in percutan coronary intervention and acute coronary syndrome [J].Ann Pharmacother, 2003, 37: 860-875.
  • 3FUSTER V, BADIMON L, BADIMON J J, et al.The pathogenesis of coronary artery disease and the acute coronary syndromes [J]. N Engl J Med, 1992,326: 242- 250.
  • 4The Restore Investigators. Effects of platelet Glycoprotein Ⅱb/Ⅲa Blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty[J]. Circulation ,1997, 96: 1445-1453.
  • 5The Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-PLUS) Study Investigators.Inhibition of the platelet glycoprotein Ⅱb/Ⅲ a receptor with tirofiban in unstable angina and non-Q-wave rnyocardial infarction[J]. N Engl J Med, 1998, 338:1488-1497.
  • 6BOERSMA E, HARRINGTON R A, MOLITERNO D J, et al. Platelet glycoprotein Ⅱb/Ⅲa inhibitors in acute coronary syndromes: a meta-analysis of all major randomised clinical trials[J]. Lancet, 2002, 359:189-198.
  • 7TCHENG J E, ELLIS S G, GEORGE B S, et al.Pharmacodynamics of chimetic glycoprotein Ⅱb/Ⅲa integrin antiplatelet antibody Fab TEs in high-risk coronary angioplasty[J]. Circulation, 1994, 90:1757-1764.

共引文献70

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部