摘要
目的了解女性宫颈炎患者支原体感染及其对药物的耐药情况,为临床合理用药提供实验依据。方法从265例宫颈炎患者分泌物中分离培养支原体,对培养的支原体进行药物敏感试验。结果共从147例患者分泌物中分离到支原体,分离率为55.47%;强力霉素对支原体的抗菌活性较差,大环类酯类抗生素对Uu有较好的抗菌活性,以交沙霉素的抗菌活性最强,但人型支原体对大环内酯类抗生素存在较高的耐药性。环丙沙星和诺氟沙星对Uu和Mh的抗菌活性弱于依诺沙星和司帕沙星的抗菌活性。结论宫颈炎患者中存在较高的支原体感染率,可用大环内酯类抗生素治疗Uu引起的感染,氟喹诺酮类抗生素中的依诺沙星和司帕沙星对Uu和Mh均有较好的抗菌活性。
Objective To acquire the information about Mycoplasma infection in genitourinary tract of cervicitis patients and the resistance to antibiotics,to provide experimental data for reasonable application of antibiotics clinically.Methods Mycoplasmas were cultured from 265 Cases cervicitis patients,drug sensitivity test on 147 Mycoplasma-positive cervicitis cases was conducted.Results Mycoplasma were isolated from 147 Cases cervicitis patients,the isolated rate is 55.47%.Doxycycline has bad antibacterial activity to mycoplasma,and Josamycin,the Macrolides antibiotics,were the most active against ureaplasma urealyticum（Uu）,but Mh has varying degree of resistance to Macrolides antibiotics.Sparfloxacin and Enoxacin had better antibacterial activity to Uu and Mycoplasma hominis（Mh） than that of Ciprofloxacin and Norfloxacin.Conclusion There are higher Mycoplasma infection rate for cervicitis patients,macrolides can be used in the treatment of Uu infection.Sparfloxacin and Enoxacin had better antibacterial activity to Uu and Mh.
出处
《当代医学》
2010年第26期12-14,共3页
Contemporary Medicine
关键词
支原体
药敏试验
宫颈炎
Mycoplasma
Drug sensitivity test
Cervicitis
