期刊文献+

黄芩苷调节高脂饲养大鼠肝脏脂质代谢及其机制 被引量:4

Baicalin regulates lipid metabolism in high-fat feeding SD rat liver and the mecbanism involves modulation of AMPK-alpha pathway
原文传递
导出
摘要 近年来,非酒精性脂肪性肝病(NAFLD)发病率有逐年上升的趋势,但目前对NAFLD尚无有效的疗法,减少肝脏细胞内脂质含量有望减轻高脂饮食对肝脏的危害。有研究结果表明,黄芩苷对肝脏具有较好的保护作用,
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2010年第9期711-712,共2页 Chinese Journal of Hepatology
关键词 蛋白激酶类 乙酰CoA羧化酶 黄芩苷 脂质代谢 Protein kinases Acetyl-CoA catboxylase Baicalin Lipid metabolism
  • 相关文献

参考文献1

二级参考文献37

  • 1Boden G. Obesity and free fatty acids. Endocrinol Metab Clin North Am 2006; 37: 635-46.
  • 2Festi D, Colec'chia A, Sacco T, Bondi M, Roda E, Marchesini G. Hepatic steatosis in obese patients: clinical aspects and prognostic significance. Obes Rev 2004; 5: 27-42.
  • 3Akbar DH, KawtherAH. Non-alcoholic fatty liver disease and metabolic syndrome: what we know and what we don't know. Med Sci Monit 2006; 12: RA23-RA26.
  • 4ClarkJM, DiehlAM. Nonalcoholic fatty liver disease: an underrecognized cause of cryptogenic cirrhosis. JAMA 2003; 289: 3000-4.
  • 5Wieckowska A, McCullough AJ, Feldstein AE. Noninvasive diagnosis and monitoring of nonalcoholic steatohepatitis: present and future. Hepatology 2007; 46: 582-9.
  • 6Adams LA, Angulo P, Lindor KD. Nonalcoholic fatty liver disease. CMAJ 2005; 172: 899-905.
  • 7Younossi ZM. Review article: current management of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. Aliment Pharmacol Ther 2008; 28: 2-12.
  • 8Marcaurelle LA, Johannes CW. Application of natural product-inspired diversity-oriented synthesis to drug discovery. Prog Drug Res 2008; 66: 189-216.
  • 9Lin CL, HuangHC, Lin JK. Theaflavinsattenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells. J Lipid Res 2007; 48: 2334-43.
  • 10Zang M, Xu S, Maitland-Toolan KA, Zuccollo A, Hou X, Jiang B, et al. Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice. Diabetes 2006; 55: 2180-91.

共引文献19

同被引文献36

引证文献4

二级引证文献21

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部