摘要
目的探讨子宫切除对保留双侧与单侧卵巢对卵巢功能的影响。方法选取因子宫良性病变在４５岁前行子宫切除，保留双侧卵巢的３６例为Ａ组，保留单侧卵巢的２５例为Ｂ组（两组术后时间均为５年），选取正常妇女２３例为对照组（Ｃ组）。询问更年期症状，测定ＦＳＨ、ＬＨ、Ｅ２、Ｐ值，同时选择３组中的部分病人行ＢＢＴ测定。结果与Ｃ组比较，Ａ组更年期症状２／３有显著性差异（Ｐ＜０．０５），Ｂ组所有症状均有显著性和极显著性差异（Ｐ＜０．０５，Ｐ＜０．０１）。同时与Ｃ组比较，Ａ组ＦＳＨ、ＬＨ上升，Ｅ２、Ｐ下降（均为Ｐ＜０．０５），Ｂ组ＦＳＨ、ＬＨ上升与Ｐ下降（Ｐ＜０．０５），Ｅ２进一步下降（Ｐ＜０．０１）。ＦＳＨ与ＬＨ同时上升的Ａ组占２５％，Ｂ组占４６．７％，Ｃ组为０。ＢＢＴ测定中，ＢＢＴ双相的Ａ与Ｃ比较，Ｐ＞０．０５；Ｂ与Ｃ比较，Ｐ＜０．０５。结论４５岁前行子宫切除，术后５年以上的不仅保留单侧卵巢的功能严重衰退，即使保留双侧卵巢其功能也明显减退。
Objectives To investigate the changes of ovarian function after uterectomy in women with unilateral ovary or bilateral ovarium reserved.Methods 61 women who accepted uterectomy before 45 years old because of various kinds of genecological deseases were divided into two groups (postoperative time≥5years).Group A 36 cases with bilateral ovarium reserved,group B 25 cases with unilateral ovary reserved.23 normal women were also enrolled as group C.Climaceric symptoms were asked and the serum levels of FSH、LH、E 2、P were assayed.The basal body temperature (BBT) of some patients among the three groups were measured at the same time.Results Contrasted with group C,the expression of 2/3 climacteric symptoms in patients of group A was significant ( P <0.05) and the expression of all climacteric symptoms in patients of group B was significant or quite significant ( P <0.05, P <0.01).The serum FSH、LH levels in group A and B increased higher than that of group C ( P <0.05).Contrast with group C,the serum levels of P decreased in both group A and C( P <0.05) and the serum E 2 levels decreased in group A ( P <0.05) and group B ( P <0.01).The percentages of patients with serum FSH and LH levels increasing simutaneously in group A、B、C were 25%,46.7% and 0% respectively.There was no difference between group A and C about the appearance of diphasic basal tempreture ( P >0.05) and there was significant difference between group B and C ( P <0.05).Conclusions The function of ovary had declined apparently over five years since accepted uterectomy (age<45 years) either in women with unilated ovary or bilateral ovarium reserved.
出处
《宁夏医学杂志》
CAS
1999年第7期394-395,共2页
Ningxia Medical Journal
