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颅咽管瘤全切除术 被引量:12

Total removal of craniopharyngioma
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摘要 目的探索手术全切除颅咽管瘤的有效方法。方法30例颅咽管瘤患者,肿瘤位于鞍上者17例,进入第三脑室内者11例,鞍上鞍内者2例。肿瘤钙化18例,肿瘤完全囊性变者5例,部分囊性变者17例,完全实性者8例;肿瘤直径20~60cm,平均334cm。均在全麻下翼点入路,术中根据肿瘤位置,从视交叉前间隙,视神经外侧间隙和颈内动脉外侧间隙切除肿瘤。术中除注意第三脑室底神经结构保护外,应防止从颈内动脉、后交通动脉、大脑后动脉及基底动脉发出的穿通动脉的损伤。结果除1例二次手术患者近全切除外,29例均达到肿瘤全切除。术后27例参加日常工作,1例需要生活照顾,2例死亡,其中1例死于尿崩症,1例因误吸死亡。结论术中保护下丘脑神经结构和避免其细小穿通动脉的损伤,对安全切除鞍上和三脑室内颅咽管瘤起重要作用。 Objective To study the better method of surgical managementof craniopharygioma. Methods We treated 30 patients with craniopharyngioma ranged in age from 15 to 55 years (mean: 3413years old). MR image showed that the tumors diameter varied from 20 cm to 60 cm (mean, 334 cm). 17 patients had the tumor in suprasellar region, 11 had tumor extention in the third ventricle 2 and had the tumor down to insellar. Complete cystic tumor was seen in 5 patients, partial cystic tumor in 17, and solid tumor in 8. Calcified tumor was found in 18 patients. Frontal temporal craniotomy was performed in all patients. The tumor was dissected in the parachiasmal opticocarotid,carotidotentorial spaces and lamina terminals. Great attention was paid to the preservation of the perforating arteries from the carotid, posterior and anterior communication and anterior choroidal arteries to the structure of the hypothalamus. The solid portion of the tumor was removed by piecemeal. Results The tumor was totally removed in 29 patients and subtotally removed in 1 patient by second surgery. Followup showed that 27 patients resamed normal life, 1 patient needed assistance, 1 died 7 days after surgery from inhalation asphyxia, and 1 died from complications of diabetes insipidus. Conclusions Many different surgical approaches can be used in the treatment of carniopharyngioma according to the localization and extension of the tumor. However, avoidance of the neural structures injury in the third ventricle and preservation of the perforating anteries to hypothalamus are essential to achieving a good surgical result.
出处 《中华外科杂志》 CAS CSCD 北大核心 1999年第6期355-357,共3页 Chinese Journal of Surgery
关键词 颅咽管瘤 神经外科手术 全切除术 CraniopharygiomaNeurosurgery
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参考文献4

  • 1张纪 段国升 等.90例颅咽管瘤的显微外科积极手术[J].中华医学杂志,1995,75:66-68.
  • 2石祥恩,中华神经外科杂志,1996年,12卷,335页
  • 3张纪,中华医学杂志,1995年,75卷,66页
  • 4石祥恩,王忠诚,吴斌.翼点入路手术切除颅咽管瘤[J].中华神经外科杂志,1996,12(6):335-335. 被引量:28

二级参考文献3

  • 1张纪,中华医学杂志,1995年,11卷,66页
  • 2许百男,中华神经外科杂志,1993年,9卷,327页
  • 3朱贤立,中华神经外科杂志,1992年,8卷,11页

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