摘要
目的探讨血浆抑制素（ｉｎｈｉｂｉｎ，ＩＮＨ）在异位妊娠中的含量变化及临床意义。方法设置宫内妊娠组（２６例）和异位妊娠组（１８例），并设对照组，应用改良的ＩＮＨ放射免疫测定（ＲＩＡ）方法测定早期宫内及异位妊娠血浆ＩＮＨ含量变化，并将血浆βｈＣＧ与ＩＮＨ浓度进行相关性分析。结果１．异位妊娠组血浆ＩＮＨ和βｈＣＧ均值小于宫内妊娠组，差异显著，Ｐ值均＜０．０５；２．宫内妊娠组血浆ＩＮＨ与βｈＣＧ间呈显著相关关系：ｒ宫内＝０．４８７，Ｐ＜０．０２５；异位妊娠组，两者间无相关性，ｒ异位＝０．２８１，Ｐ＞０．０５。结论联合监测血浆ＩＮＨ及βｈＣＧ可作为异位妊娠的辅助诊断；
Objective To
investigate the changes of inhibin content in ectopic pregnancy and its clinical significance.
Methods Twenty six cases of intrauterine pregnancy and Eighteen cases of ectopic pregnancy
were choosen arbitrarily. Modified inhibin radioimmunoassay was used to measure the
changes of plasma inhibin contents in both intrauterine and ectopic pregnancy. The correlation
between serum β hCG and inhibin was analysed statistically. Results 1. The mean values of
plasma levels of inhibin and β hCG in ectopic pregnancy were both lower than those in
intrauterine pregnancy, the difference was significant, P <0.05; 2. In intrauterine pregnancy
the correlation between plasma levets of inhibin and β hCG significant, r= 0.487, P <0.025;
No correlation was present between plasma inhibin and β hCG in ectopic pregancy, r= 0.281,
P >0.05.Conclusions Monitoring of both plasma levels of inhibin and β hCG would be helpful
in the diagnosis of ectopic pregnancy and in evaluation of the condition of gestational corpora
lutea and embryonic development.
出处
《上海医学》
CAS
CSCD
北大核心
1999年第6期358-360,共3页
Shanghai Medical Journal
关键词
异位妊娠
Β-HCG
血浆抑制素
Inhibin Ectopic pregnancy Human
chorionic gonadotropin β hCG subunit (β hCG).
