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数字化X线立体定位真空辅助活检术诊断T_0期乳腺癌的临床研究 被引量:6

Clinical Research of Digital X-ray Stereotactic Vacuum-assisted Biopsy for Stage T_o Breast Cancer
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摘要 目的:探讨数字化x线立体定位真空辅助活检术对临床触诊阴性乳腺癌的早期诊断价值。方法:2007年10月至2009年9月南方医科大学附属深圳市妇幼保健院应用Lorad数字化钼靶机和Lorad Multicare俯卧式活检系统引导Vacora对243例临床不可触及的可疑病灶(BI-RADS评级为Ⅳ级及以上)行真空辅助活检术。结果:活检成功率为99.6%(242/243),手术时间20~60min,中位时间32min。术后病理:乳腺导管内癌21例、导管内癌伴微浸润7例、浸润性导管癌2例、浸润性小叶癌1例:病理分期:0期21例、Ⅰ期9例、ⅡA期1例;乳腺导管上皮不典型增生22例,占活检总数的9.1%。术后出现皮下瘀斑15例、血肿形成11例,未见其他严重手术并发症。结论:数字化俯卧式穿刺活检定位系统引导Vacora真空负压辅助活检系统(10G)对钼靶下的乳腺微小病灶的活检术,具有活检定位精准、手术成功率高、创伤小等特点,对T_0期乳腺癌的早期诊断有较高的临床应用价值。 Objective: T0 evaluate the advantages of stereotactic biopsy with vacuum-assisted biopsy device in early diagnosis of Stage-T0 breast cancer patients. Methods: From October 2007 to September 2009, The Vacora vacuum-assisted biopsy device was conducted in 243 cases with clinically non-palpable suspicious lesions (Stage-Ⅳ and above by BI-RADS rating) in our hospital. Stereotactic biopsy was performed with Lorad Multicare Prone Breast Biopsy System with digital imaging capabilities (StereoGuide with Digital Spot Mammography; LoRad, US). Results: The success rate of biopsy was 99.6% (242/ 243). The time of surgery ranged from 20 to 60 minutes, with the median time of 32. Post-operative pathological examination demonstrated that ductal carcinoma in situ occurred in 21 of the cases, ductal carcinoma in situ with micro-invasion in 7 cases, infiltrating duct carcinoma in 2 cases, and invasive Iobular carcinoma in 1 case. Based on the pathologic TNM staging, there were 21 cases with Stage-0, 9 cases with Stage-I, and 1 case with Stage-IIA. Atypical hyperplasia was found in 21 cases, accounting for 9.1% of the total undergoing the biopsy. Postoperative complications included subcutaneous ecchymosis in 15 cases and hematoma in 11 cases. No other severe complications were found. Conclusion: The MultiCare digital intervention system guided Vacura vacuum biopsy is valuable in assessing the impalpable breast lesions in early diagnosis of Stage-T0 breast cancer patients.
出处 《中国肿瘤临床》 CAS CSCD 北大核心 2010年第17期991-993,共3页 Chinese Journal of Clinical Oncology
基金 深圳市科技局项目资助(编号:200703268)
关键词 数字化X线立体定位 真空辅助活检 乳腺癌 早期诊断 Digital X-ray stereotaxis Vacuum-assisted biopsy Breast cancer Early diagnosis
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参考文献13

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