摘要
目的探讨血浆β-内啡肽、血清皮质醇及血糖含量变化对新生儿缺氧缺血性病的临床意义。方法采用放射免疫法、氧化酶法测定61例新生儿缺氧缺血性脑病（HIE）患儿β-内啡肽（β-EP）、皮质醇（COR）、血糖的含量和22例重症患儿的动态观察，及对例健康足月儿的正常对照测定。结果β-EP、COR中重度组显著高于对照组P＜0．01。22例重度组动态观察第3、3天β-EP、COR与对照组相比还显著高于对照组P＜0．01或P＜0，05。重度组22例中8例高血糖患儿β-EP、COR含量均高于14例非高血糖患儿。结论β-EP、COR、血糖显著升高可作为HIE预后不良标志之一。
Objective To expiore the changes and sighificane of β - EP , corticoid (COR) and blood sugar in neonate with hypoxic ischemic encephalopathy (HIE). Methods Observe 22 intensive case of 61 as HIE in neonate with β - EP, COR and blood sugar 20 nomal case were observed as contrast at the same time ,Resuits 1 The level of β - EP, COR of case are higher than normal (P <0.01 ). 2The level of β - EP, COR of 8 case with high blood sugar are higher than the other 14 case without high blood sugar . Conclusion The higher level of β- EP,COR and blood sugar may be the sign of bad proghosis f HIE.
出处
《中国急救医学》
CAS
CSCD
北大核心
1999年第6期342-343,共2页
Chinese Journal of Critical Care Medicine
