摘要
目的:评价运动试验后QTc离散度(QTcd)在老年陈旧性心肌梗塞中的临床意义。方法:对64例老年陈旧性心肌梗塞患者(心梗组)进行活动平板运动试验、24h动态心电图、超声心动图检测及临床随访平均2412±77月;并以30例健康老年人为对照组。结果:心梗组运动试验前为QTcd(4021±1521)ms,运动试验后为(5937±2017)ms(P<0.01);对照组QTcd运动试验前、后比较差异均无显著性(P>0.05);两组QTcd运动试验前比较差异无显著性(P>0.05),但运动试验后心梗组QTcd较对照组明显增高(P<0.01)。运动试验后心梗组QTcd>50ms异常者室壁节段性运动异常、室壁瘤、心功能级别Ⅲ级和Lown氏室性心律失常等级Ⅲ级以上的发生率均显著性高于QTcd<50ms正常组。随访期间心梗组中,QTcd异常者发生心脏性猝死5例,而正常者未发生心脏性猝死。结论:运动试验后QTcd是预测陈旧性心肌梗塞室性心律失常及心性猝死重要指标之一。
Objective: This study was aimed to evaluate clinical significance of Q Tc dispersion after exercise in aged patients with old myocardial infarction. Method: Sixty four aged patients with old myocardial infarction(infarction group) were examined by treadmill exercise, dynamic electrocardiography, echocardiography, and were followed up for average of 24.12±7.7 months. 30 healthy aged persons were served as control group. Results: Compared with that (40.21±15.21ms) before exercise, Q Tc dispersion (59.37±20.17ms) was increased significantly after exercise in infarction group( P <0.01). But no significant difference was found in Q Tc dispersion of control group before and after exercise(34.70±12.29ms vs 38.91±13.62ms P >0.05). In infarction group, occurrence of abnormal contraction of left ventricular wall, aneurysms, NYHA Ⅲ class and >Ⅲ class of Lown's ventricular arrhythmia classification was significantly higher in Q Tcd>50ms patients than that in Q Tcd<50ms ones( P <0.05). It was found that 5 patients died of cardiac sudden death in Q Tcd>50ms patients and no one died of cardiac sudden death in Q Tcd<50ms ones. Conclusion: The Q Tc dispersion after exeroise is an important index to predict ventricular arrhythmia and cardiac death in the patients with old myocardial infarction.
出处
《湖南医科大学学报》
CSCD
1999年第3期248-250,共3页
Bulletin of Hunan Medical University
关键词
陈旧性
心肌梗塞
QT离散度
老年人
Q Tc dispersion
old myocardial infarction
ventricular arrhythmia
cardiac sudden death