摘要
目的探讨中医综合疗法对双肾脂肪细胞形态及血清高密度脂蛋白水平的影响作用。方法从80只SD大鼠中选取体重相近大鼠70只,随机分成正常对照组、模型对照组、阳性药物对照组、针灸治疗组、埋线治疗组、中药治疗组、综合治疗组,每组10只。采用营养肥胖造模方法复制肥胖模型大鼠,干预前、后,检测各组大鼠双肾脂肪细胞形态变化及血清高密度脂蛋白含量。结果①形态观察结果:模型对照组双肾脂肪细胞体积大于正常对照组,综合疗法组与模型治疗组比较,细胞形态缩小,脂肪细胞数减少;②血清高密度脂蛋白检测结果:模型对照组血清高密度脂蛋白低于正常对照组(P<0.01),综合治疗组血清高密度脂蛋白水平明显高于模型治疗组(P<0.01),与针灸治疗组及穴位埋线治疗组有明显统计学意义(P<0.05)。结论中医综合治疗较其他治疗方法比较具有更好减肥降脂功效,其减肥作用可能与升高血清高密度脂蛋白,降低血清总胆固醇和甘油三酯水平有关。
Objective To explore the effect of Chinese medical combined therapy on high density lipoprotein and lipocyte morpha of obese rats.Methods70 rats,which had the similar weight from the 80 rats,were divided into normal,model,positive medical,acupuncture,catgut-embedding-therapy,Chinese-medical,combined treatment groups,and rorats each group.The model of alimentary obesity was established,and the blood High Density Lipoprotein and lipocyte＇s morpha were compared before and after treatment.ResultsVolume of the kidney adipose tissue in model group was bigger than that of normal group.Compared with the combined-treatment group and model group,lipocyte＇s morpha dwindled and the number of lipocyte reduced in combined-treatment group.Serum high density lipoprotein in model group was higher than that in normal group（P0.01）.Serum high density lipoprotein in combined-treatment group is higher than it in the normal group（P0.05）.ConclusionChinese medical combined treatment has a good effect on adiposity,its mechanism maybe related to the increase of serum high density lipoprotein and the decrease of serum total cholesterol and triglyceride.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2010年第9期2315-2317,共3页
Lishizhen Medicine and Materia Medica Research
基金
广西壮族自治区自然科学基金(No.0832176)
关键词
肥胖
中医综合疗法
脂肪细胞
形态
高密度脂蛋白
Adiposity
Chinese medical combined treatment
Lipocyte
Morpha
High-density lipoprotein
